0000000001277028
AUTHOR
Brenda Palomar-de Lucas
Click amidations, esterifications and one–pot reactions catalyzed by Cu salts and multimetal–organic frameworks (M–MOFs)
Amides and esters are prevalent chemicals in Nature, industry and academic laboratories. Thus, it is not surprising that a plethora of synthetic methods for these compounds has been developed along the years. However, these methods are not 100% atom economical and generally require harsh reagents or reaction conditions. Here we show a “spring–loaded”, 100% atom–efficient amidation and esterification protocol which consists in the ring opening of cyclopropenones with amines or alcohols. Some alkyl amines react spontaneously at room temperature in a variety of solvents and reaction conditions, including water at different pHs, while other alkyl amines, aromatic amines and alcohols react in th…
CCDC 2090411: Experimental Crystal Structure Determination
Related Article: Rossella Greco, Estefanía Tiburcio, Brenda Palomar-De Lucas, Jesús Ferrando-Soria, Donatella Armentano, Emilio Pardo, Antonio Leyva-Pérez|2022|Mol.Catal.|522|112228|doi:10.1016/j.mcat.2022.112228