0000000001279113
AUTHOR
J. Marton
The impact of conversion on the risk of major complication following laparoscopic colonic surgery: an international, multicentre prospective audit.
BACKGROUND: Laparoscopy has now been implemented as a standard of care for elective colonic resection around the world. During the adoption period, studies showed that conversion may be detrimental to patients, with poorer outcomes than both laparoscopic completed or planned open surgery. The primary aim of this study was to determine whether laparoscopic conversion was associated with a higher major complication rate than planned open surgery in contemporary, international practice.METHODS: Combined analysis of the European Society of Coloproctology 2017 and 2015 audits. Patients were included if they underwent elective resection of a colonic segment from the caecum to the rectosigmoid jun…
Study of doubly strange systems using stored antiprotons
Bound nuclear systems with two units of strangeness are still poorly known despite their importance for many strong interaction phenomena. Stored antiprotons beams in the GeV range represent an unparalleled factory for various hyperon-antihyperon pairs. Their outstanding large production probability in antiproton collisions will open the floodgates for a series of new studies of systems which contain two or even more units of strangeness at the PANDA experiment at FAIR. For the first time, high resolution gamma-spectroscopy of doubly strange Lambda Lambda-hypernuclei will be performed, thus complementing measurements of ground state decays of Lambda Lambda-hypernuclei at J-PARC or possible …
Evaluating the incidence of pathological complete response in current international rectal cancer practice: the barriers to widespread safe deferral of surgery
INTRODUCTION: The mainstay of management for locally advanced rectal cancer is chemoradiotherapy followed by surgical resection. Following chemoradiotherapy, a complete response may be detected clinically and radiologically (cCR) prior to surgery or pathologically after surgery (pCR). We aim to report the overall complete pathological response (pCR) rate and the reliability of detecting a cCR by conventional pre-operative imaging.METHODS: A pre-planned analysis of the European Society of Coloproctology (ESCP) 2017 audit was performed. Patients treated by elective rectal resection were included. A pCR was defined as a ypT0 N0 EMVI negative primary tumour; a partial response represented any r…
An international multicentre prospective audit of elective rectal cancer surgery; operative approach versus outcome, including transanal total mesorectal excision (TaTME)
Introduction: Transanal total mesorectal excision (TaTME) has rapidly emerged as a novel approach for rectal cancer surgery. Safety profiles are still emerging and more comparative data is urgently needed. This study aimed to compare indications and short-term outcomes of TaTME, open, laparoscopic, and robotic TME internationally. Methods: A pre-planned analysis of the European Society of Coloproctology (ESCP) 2017 audit was performed. Patients undergoing elective total mesorectal excision (TME) for malignancy between 1 January 2017 and 15 March 2017 by any operative approach were included. The primary outcome measure was anastomotic leak. Results: Of 2579 included patients, 76.2% (1966/257…
The DIRC detectors at the PANDA experiment
PANDA is an experiment at the new FAIR facility at GSI and will, among other physics goals,\ud perform charmonium spectroscopy and search for gluonic excitations using high luminosity antiproton beams up to 15 GeV/c. A high performance particle identification system applying DIRC\ud detectors will allow pion/kaon separation up to 4 GeV/c. A Barrel DIRC with fused silica radiator bars or plates will surround the target at a radial distance of 48 cm and will cover a polar\ud angle range of 22 to 140 degrees; a novel Endcap Disk DIRC built of a segmented fused silica\ud disk of 210 cm diameter will be installed in the forward region to cover the polar angles from\ud 5 to 22 degrees. The design…
New developments of the PANDA Disc DIRC detector
The DIRC principle (Detection of Internally Reflected Cherenkov light) allows a very compact\ud approach for particle identification detectors. The PANDA detector at the future FAIR facility at\ud GSI will use a Barrel-DIRC for the central region and a Disc DIRC for the forward angular region\ud between 5◦\ud and 22◦\ud . It will be the first time that a Disc DIRC is used in a high performance 4π\ud detector. To achieve this aim, different designs and technologies have been evaluated and tested.\ud This article will focus on the mechanical design and integration of the Disc DIRC with respect to\ud the PANDA environment.
Frontend Electronics for high-precision single photo-electron timing
The next generation of high-luminosity experiments requires excellent particle identification detectors, which calls for imaging Cherenkov counters with fast electronics to cope with the expected hit rates. A Barrel DIRC will be used in the central region of the Target Spectrometer\ud of the planned PANDA experiment at FAIR. A single photo-electron timing resolution of better\ud than 100 ps RMS is required for the Barrel DIRC to disentangle the complicated patterns created\ud on the image plane. R&D studies have been performed to provide a design based on the TRB3\ud readout using FPGA-TDCs with a typical precision of 10 ps RMS and custom frontend electronics with high-bandwidth pre-amp…