0000000001284091

AUTHOR

Daniel Schäfer

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The serine/threonine kinase 33 is present and expressed in palaeognath birds but has become a unitary pseudogene in neognaths about 100 million years…

2015

Background Serine/threonine kinase 33 (STK33) has been shown to be conserved across all major vertebrate classes including reptiles, mammals, amphibians and fish, suggesting its importance within vertebrates. It has been shown to phosphorylate vimentin and might play a role in spermatogenesis and organ ontogenesis. In this study we analyzed the genomic locus and expression of stk33 in the class Aves, using a combination of large scale next generation sequencing data analysis and traditional PCR. Results Within the subclass Palaeognathae we analyzed the white-throated tinamou (Tinamus guttatus), the African ostrich (Struthio camelus) and the emu (Dromaius novaehollandiae). For the African os…

GenomeEvolutionSerine/threonine kinase 33Protein Serine-Threonine KinasesGenetic redundancy570 Life sciencesBirdsEvolution MolecularPseudogeneGene Expression RegulationVertebratesGeneticsAnimalsNon-orthologous gene displacementAvesResearch ArticleBiotechnology570 Biowissenschaften
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