0000000001287883

AUTHOR

Helen Griffiths

showing 3 related works from this author

Does age matter?: A comparison of health‐related quality of life issues of adolescents and young adults with cancer

2018

Objective:Health‐related quality of life (HRQoL) concerns of adolescents and young adults (AYAs) aged 14–25 years were compared with those of older adults (26–60 years) with cancer.Methods:AYAs and older adults receiving curative intent treatment or supportive palliative care for cancer were recruited from eight research centres across Europe. Participants used a rating scale to score the relevance and importance of a list of 77 issues covering 10 areas of HRQoL concern: symptoms; activity restrictions; social; emotional; body image; self‐appraisals; outlook on life; lifestyle; treatment‐related and life beyond treatment.Results:HRQoL issues were reviewed by 33 AYAs and 25 older adults. Sev…

GerontologyAdultMalePalliative careActivities of daily livingAdolescentmedia_common.quotation_subjectHealth StatusEmotionsPsycho-oncologyFertility03 medical and health sciencesYoung Adult0302 clinical medicineQuality of life (healthcare)Rating scaleNeoplasmsActivities of Daily LivingBody ImageMedicineHumans030212 general & internal medicineYoung adultLife Stylemedia_commonbusiness.industryAge FactorsMiddle AgedSocial ParticipationSelf ConcepthumanitiesOncologyAttitude030220 oncology & carcinogenesisQuality of LifeFemalebusinessPsychosocialRare cancers Radboud Institute for Health Sciences [Radboudumc 9]
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A life put on pause: an exploration of the health-related quality of life issues relevant to adolescents and young adults with cancer

2018

Purpose: in recent years, the assessment of health-related quality of life (HRQoL) has been recognized as particularly informative to health care providers. For adolescents and young adults (AYAs), the impact of a cancer diagnosis and subsequent treatment is likely to be distinct from other age groups given the unique and complex physical and psychosocial challenges of this developmental phase. The objective of this study was to capture the HRQoL issues described by AYAs with cancer using thematic analysis.Methods: semi-structured interviews were carried out with 45 AYAs aged 14-25 years from 6 countries. Results: the most prevalent cancers presented were leukemia (n=12) and lymphoma (n=8).…

Gerontologybusiness.industryNauseaFamily lifehumanities03 medical and health sciencesAll institutes and research themes of the Radboud University Medical Center0302 clinical medicineQuality of life (healthcare)Oncology030220 oncology & carcinogenesisPediatrics Perinatology and Child HealthMedicineAnxiety030212 general & internal medicineYoung adultmedicine.symptomThematic analysisbusinessPsychosocialDepression (differential diagnoses)Rare cancers Radboud Institute for Health Sciences [Radboudumc 9]
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European contribution to the study of ROS : A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

2017

WOS: 000410470000009

0301 basic medicinereactive oxygen species ; reactive nitrogen species ; redox signaling ; oxidative stress ; antioxidants ; redox therapeuticsRedox signalingInternational CooperationSMOOTH-MUSCLE-CELLS[SDV]Life Sciences [q-bio]Clinical BiochemistryISCHEMIA-REPERFUSION INJURYReviewddc:616.07Bioinformaticsmedicine.disease_causeBiochemistryAntioxidants0302 clinical medicineENDOPLASMIC-RETICULUM STRESSCost actionlcsh:QH301-705.5ComputingMilieux_MISCELLANEOUSmedia_commonlcsh:R5-920Redox therapeuticsReactive nitrogen species3. Good healthVariety (cybernetics)MANGANESE SUPEROXIDE-DISMUTASECHRONIC GRANULOMATOUS-DISEASERisk analysis (engineering)ddc:540lcsh:Medicine (General)Oxidation-ReductionSignal TransductionSocieties ScientificPULMONARY ARTERIAL-HYPERTENSIONMedicinaEstrès oxidatiuBiology03 medical and health sciencesAntioxidants ; Oxidative Stress ; Reactive Nitrogen Species ; Reactive Oxygen Species ; Redox Signaling ; Redox TherapeuticsJournal Articlemedicinemedia_common.cataloged_instanceAnimalsHumans[CHIM]Chemical SciencesEuropean UnionEuropean unionNITRIC-OXIDE SYNTHASETANDEM MASS-SPECTROMETRYMolecular BiologyMITOCHONDRIAL OXIDATIVE STRESSGROWTH-FACTOR-BETAOrganic ChemistryDisease progressionBiology and Life SciencesOxidation reductionManganese Superoxide Dismutase030104 developmental biologylcsh:Biology (General)Oxidative stressReactive oxygen species030217 neurology & neurosurgeryOxidative stressRedox biology
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