0000000001296358

AUTHOR

S. Ferrando

showing 2 related works from this author

Risk for non-AIDS-defining and AIDS-defining cancer of early versus delayed initiation of antiretroviral therapy

2021

BACKGROUND: Immediate initiation of antiretroviral therapy (ART) regardless of CD4 cell count reduces risk for AIDS and non-AIDS-related events in asymptomatic, HIV-positive persons and is the standard of care. However, most HIV-positive persons initiate ART when their CD4 count decreases below 500 × 10 9 cells/L. Consequences of delayed ART on risk for non-AIDS-defining and AIDS-defining cancer, one of the most common reasons for death in HIV, are unclear. OBJECTIVE: To estimate the long-term risk difference for cancer with the immediate ART strategy.DESIGN: Multinational prospective cohort study.SETTING: The D:A:D (Data collection on Adverse events of anti-HIV Drugs) study, which included…

MaleHIV AIDSHIV Infections0302 clinical medicineInterquartile rangeRisk FactorsNeoplasmsMedicine030212 general & internal medicineProspective StudiesProspective cohort study0303 health sciencesIncidenceAbsolute risk reductionDrugsGeneral MedicineMiddle AgedViral LoadAntiretroviral therapy3. Good healthAIDSCancer treatmentPrevention policy and public healthCohortInfectious diseasesCohort studiesFemaleViral loadAdultmedicine.medical_specialtyAnti-HIV AgentsHIV Infections/drug therapySocio-culturaleTime-to-Treatment03 medical and health sciencesAcquired immunodeficiency syndrome (AIDS)SDG 3 - Good Health and Well-beingInternal medicineInternal MedicineHumansAdverse effect030306 microbiologybusiness.industryHIVCancermedicine.diseaseCD4 Lymphocyte CountCancer.Anti-HIV Agents/therapeutic use[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiebusinessNeoplasms/epidemiologyAnnals of Internal Medicine
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Effectiveness of a project to prevent HIV vertical transmission in the Republic of Congo

2013

OBJECTIVES: To evaluate the effectiveness of a prevention programme against the vertical transmission of HIV in a resource-limited setting and to investigate variables associated with compliance. PATIENTS AND METHODS: The Kento-Mwana project (2005-2008) provided counselling, serological and biomolecular testing and prophylaxis/therapy to HIV-positive pregnant women and their children attending four antenatal clinics in Pointe Noire, Republic of Congo. Expected and actual rates of vertical transmission of HIV were compared. Univariate and multivariate analyses were performed in order to identify variables associated with non-compliance. RESULTS: The observed transmission rate in the group wh…

MaleInfectious Disease TransmissionPMTCTHuman immunodeficiency virus (HIV)HIV Infectionsmedicine.disease_causeSettore MED/42 - Igiene Generale E Applicatalaw.inventionlawPregnancyVerticalPharmacology (medical)Prospective StudiesPregnancy Complications InfectiousProspective cohort studyAttrition; Drop-out; Lost to follow-up; Mother-to-child transmission; PMTCT; Congo; Female; HIV Infections; Humans; Infant; Infant Newborn; Infectious Disease Transmission Vertical; Male; Patient Acceptance of Health Care; Patient Compliance; Pregnancy; Pregnancy Complications Infectious; Prospective Studies; Health Services Research; Pharmacology; Pharmacology (medical); Infectious DiseasesInfectiousdrop-outTransmission (mechanics)Infectious DiseasesCongoFemaleHealth Services ResearchMicrobiology (medical)attritionHIV prevention; vertical transmission; republic of CongoTransmission rateHIV preventionTarget populationPrenatal caremedicineHumansLost to follow-upPharmacologylost to follow-upPregnancybusiness.industryInfant Newbornmother-to-child transmissionInfantrepublic of CongoPatient Acceptance of Health Caremedicine.diseaseNewbornInfectious Disease Transmission VerticalPregnancy ComplicationsImmunologyPatient Compliancevertical transmissionbusinessDemography
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