Structure and the metal-support interaction of the Au/Mn oxide catalysts

Gold catalysts with loading 1 and 10 wt % were-prepared by deposition precipitation method with urea over mesoporous manganese oxide, obtained through a surfactant-assisted procedure by using cetyltrimethylammonium bromide (CTAB), followed by treatment with sulphuric acid. For comparison, Au(10 wt %) was also deposited over commercial CeO2 and SiO2 supports. The materials were characterized by XRD and EXAFS at the Mn K and Au L-III edges and XPS. Moreover, the analyses were performed on the samples treated under 1%CO/He, at 250 degrees C for 90 min. The structural and surface results of the as prepared manganese oxide confirmed the formation of gamma-MnO2 along with some amorphous Mn3O4 upo…

Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids

AbstractThe prognosis of locally advanced colorectal cancer (CRC) is currently unsatisfactory. This is mainly due to drug resistance, recurrence, and subsequent metastatic dissemination, which are sustained by the cancer stem cell (CSC) population. The main driver of the CSC gene expression program is Wnt signaling, and previous reports indicate that Wnt3a can activate p38 MAPK. Besides, p38 was shown to feed into the canonical Wnt/β-catenin pathway. Here we show that patient-derived locally advanced CRC stem cells (CRC-SCs) are characterized by increased expression of p38α and are “addicted” to its kinase activity. Of note, we found that stage III CRC patients with high p38α levels display…

Relationship between structure and CO oxidation activity of ceria supported gold catalysts

Gold catalysts supported on cerium oxide were prepared by solvated metal atom dispersion (SMAD), by deposition-precipitation (DP), and by coprecipitation (CP) methods and were characterized by X-ray diffraction (XRD), temperature programmed reduction (TPR), and X-ray photoelectron spectroscopy (XPS). The catalytic activity was tested in the CO oxidation reaction. The structural and surface analyses evidenced the presence of a modified ceria phase in the case of the DP sample and the presence of pure ceria and gold metal crystallites in the case of the SMAD and CP samples. The DP sample, after a mild treatment in air at 393 K, exhibited only ionic gold, and it was very active below 273 K. By…

“Supported gold catalysrts for methane combustion: effect of support and preparation method”,

Relationship between structure and CO oxidation activity of ceria supported gold catalysts

“Co-precipitated Au-Co3O4-CeO2 catalysts for methane emissions abatement: influence of the support composition on catalytic performance and deactivation”

“Co3O4/CeO2 and Co3O4/CeO2-ZrO2 composite oxides for methane emissions abatement”