0000000001301051

AUTHOR

Marcello Maggiolini

showing 9 related works from this author

A Biocompatible Aspartic-Decorated Metal–Organic Framework with Tubular Motif Degradable under Physiological Conditions

2021

Achieving a precise control of the final structure of metal–organic frameworks (MOFs) is necessary to obtain desired physical properties. Here, we describe how the use of a metalloligand design strategy and a judicious choice of ligands inspired from nature is a versatile approach to succeed in this challenging task. We report a new porous chiral MOF, with the formula Ca5II{CuII10[(S,S)-aspartamox]5}·160H2O (1), constructed from Cu2+ and Ca2+ ions and aspartic acid-decorated ligands, where biometal Cu2+ ions are bridged by the carboxylate groups of aspartic acid moieties. The structure of MOF 1 reveals an infinite network of basket-like cages, built by 10 crystallographically distinct Cu(II…

Models MolecularBiocompatibilityMetal ions in aqueous solutionBiocompatible Materials010402 general chemistry01 natural sciencesArticleInorganic Chemistrychemistry.chemical_compoundAdsorptionAspartic acidTumor Cells CulturedHumansCarboxylatePhysical and Theoretical ChemistryMetal-Organic Frameworkschemistry.chemical_classificationAspartic AcidMolecular Structure010405 organic chemistryCombinatorial chemistry0104 chemical sciencesAmino acidchemistryMetal-organic frameworkDrug carrierInorganic Chemistry
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Differential expression of estrogen receptors (ER?/ER?) in testis of mature and immature pigs

2004

High affinity estrogen receptors (ERs) mediate estrogen action in male reproductive tissues. The objective of the present study was the immunolocalization of estrogen receptor alpha and estrogen receptor beta in immature and mature testes of pig, a species in which the role of estrogens on gonadal function is scarcely known. Testes from 3 and 18 month-old pigs were investigated. Immunohistochemistry was performed on paraffin embedded-tissues using both mouse anti-human monoclonal IgG ERalpha and IgG ERbeta 1 isoform. Western blot analysis demonstrated antibody specificity. ERalpha staining was not observed in immature testes, but it was detected in spermatogonia, spermatocytes and in the mo…

Leydig CellMaleendocrine systemmedicine.medical_specialtySwinemedicine.drug_classSomatic cellBlotting WesternImmunoenzyme TechniqueEstrogen receptorBiologyHeLa CellImmunoenzyme TechniquesWestern blotSpermatocytesInternal medicineTestismedicineAnimalsHumansEstrogen receptorEstrogen Receptor betaEstrogen receptor betaPig developmentmedicine.diagnostic_testAnimalurogenital systemEstrogen Receptor alphaLeydig CellsAntibodies MonoclonalEstrogenAgricultural and Biological Sciences (miscellaneous)SpermatogoniaSpermatocyteBlotEndocrinologyTestiEstrogenImmunohistochemistryAnatomyEstrogen receptor alphahormones hormone substitutes and hormone antagonistsHeLa CellsHumanThe Anatomical Record
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Crystallographic snapshots of host–guest interactions in drugs@metal–organic frameworks: towards mimicking molecular recognition processes

2018

We report a novel metal–organic framework (MOF) featuring functional pores decorated with hydroxyl groups derived from the natural amino acid L-serine, which is able to establish specific interactions of different natures, strengths and directionalities with organic molecules of technological interest, i.e. ascorbic acid, pyridoxine, bupropion and 17-β-estradiol, based on their different sizes and chemical natures. The ability of 1 to distinctly organize guest molecules within its channels, through the concomitant effect of different directing supramolecular host–guest interactions, enables gaining unique insights, by means of single-crystal X-ray crystallography, into the host–guest intera…

010405 organic chemistryChemistryProcess Chemistry and TechnologySupramolecular chemistrymacromolecular substances010402 general chemistryAscorbic acid01 natural sciences0104 chemical sciencesOrganic moleculesCrystallographyMolecular recognitionMechanics of MaterialsMoleculeGeneral Materials ScienceMetal-organic frameworkElectrical and Electronic EngineeringMaterials Horizons
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CCDC 1823995: Experimental Crystal Structure Determination

2018

Related Article: Marta Mon, Rosaria Bruno, Jesús Ferrando-Soria, Lucia Bartella, Leonardo Di Donna, Marianna Talia, Rosamaria Lappano, Marcello Maggiolini, Donatella Armentano, Emilio Pardo|2018|Materials Horizons|5|683|doi:10.1039/C8MH00302E

Space GroupCrystallographyCrystal SystemCrystal Structurecatena-[estra-1(10)24-triene-317-diol tris(mu-22'-[(12-dioxoethane-12-diyl)diimino]bis(3-hydroxypropanoato))-tetrakis(mu-aqua)-bis(mu-hydroxo)-calcium-hexa-copper(ii) acetonitrile solvate hexahydrate]Cell ParametersExperimental 3D Coordinates
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CCDC 1823991: Experimental Crystal Structure Determination

2018

Related Article: Marta Mon, Rosaria Bruno, Jesús Ferrando-Soria, Lucia Bartella, Leonardo Di Donna, Marianna Talia, Rosamaria Lappano, Marcello Maggiolini, Donatella Armentano, Emilio Pardo|2018|Materials Horizons|5|683|doi:10.1039/C8MH00302E

Space GroupCrystallographycatena-[tris(mu-22'-[(12-dioxoethane-12-diyl)diimino]bis(3-hydroxypropanoato))-bis(mu-hydroxo)-tetrakis(mu-aqua)-calcium-hexa-copper(ii) hexatriacontahydrate]Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1823993: Experimental Crystal Structure Determination

2018

Related Article: Marta Mon, Rosaria Bruno, Jesús Ferrando-Soria, Lucia Bartella, Leonardo Di Donna, Marianna Talia, Rosamaria Lappano, Marcello Maggiolini, Donatella Armentano, Emilio Pardo|2018|Materials Horizons|5|683|doi:10.1039/C8MH00302E

Space GroupCrystallographycatena-[tris(mu-22'-[(12-dioxoethane-12-diyl)diimino]bis(3-hydroxypropanoato))-bis(mu-hydroxo)-(mu-aqua)-triaqua-calcium-hexa-copper(ii) bis(45-bis(hydroxymethyl)-2-methylpyridin-3-ol) clathrate acetonitrile solvate pentadecahydrate]Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1823992: Experimental Crystal Structure Determination

2018

Related Article: Marta Mon, Rosaria Bruno, Jesús Ferrando-Soria, Lucia Bartella, Leonardo Di Donna, Marianna Talia, Rosamaria Lappano, Marcello Maggiolini, Donatella Armentano, Emilio Pardo|2018|Materials Horizons|5|683|doi:10.1039/C8MH00302E

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameterscatena-[bis(5-(12-dihydroxyethyl)-34-dihydroxyfuran-2(5H)-one) tris(mu-22'-[(12-dioxoethane-12-diyl)diimino]bis(3-hydroxypropanoato))-bis(mu-hydroxo)-(mu-aqua)-triaqua-calcium-hexa-copper(ii) clathrate acetonitrile solvate dodecahydrate]Experimental 3D Coordinates
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CCDC 2075709: Experimental Crystal Structure Determination

2021

Related Article: Marta Mon, Rosaria Bruno, Rosamaria Lappano, Marcello Maggiolini, Leonardo Di Donna, Jesus Ferrando Soria, Donatella Armentano, Emilio Pardo|2021|Inorg.Chem.|60|14221|doi:10.1021/acs.inorgchem.1c01701

Space GroupCrystallographycatena-[tetrakis(mu-aqua)-heptadecakis(aqua)-tri-calcium(ii) pentakis(mu-2-({[(12-dicarboxylatoethyl)carboximidato](oxidanidyl)methylidene}amino)butanedioato)-hexadecakis(aqua)-di-calcium(ii)-deca-copper(ii) tricosahectahydrate]Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1823994: Experimental Crystal Structure Determination

2018

Related Article: Marta Mon, Rosaria Bruno, Jesús Ferrando-Soria, Lucia Bartella, Leonardo Di Donna, Marianna Talia, Rosamaria Lappano, Marcello Maggiolini, Donatella Armentano, Emilio Pardo|2018|Materials Horizons|5|683|doi:10.1039/C8MH00302E

Space GroupCrystallographyCrystal Systemcatena-[2-(t-butylamino)-1-(3-chlorophenyl)propan-1-one tris(mu-22'-[(12-dioxoethane-12-diyl)diimino]bis(3-hydroxypropanoato))-bis(mu-hydroxo)-(mu-aqua)-calcium-hexa-copper(ii) clathrate docosahydrate]Crystal StructureCell ParametersExperimental 3D Coordinates
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