0000000001301241

AUTHOR

Tina Riedel

showing 5 related works from this author

Palladium(II)-Stabilized Pyridine-2-Diazotates: Synthesis, Structural Characterization, and Cytotoxicity Studies

2018

Well-defined diazotates are scarce. Here we report the synthesis of unprecedented homoleptic palladium(II) diazotate complexes. The palladium(II)-mediated nitrosylation of 2-aminopyridines with NaNO2 results in the formation of metal-stabilized diazotates, which were found to be cytotoxic to human ovarian cancer cells.

Models Molecularinorganic chemicalsCell SurvivalPyridinesPyrazine Diazohydroxidechemistry.chemical_elementAntineoplastic AgentsorganometalliyhdisteetCrystallography X-Ray010402 general chemistry01 natural sciencesInorganic ChemistryStructure-Activity Relationshipchemistry.chemical_compoundCoordination ComplexesCell Line Tumororganometallic compoundsPyridineHumansCytotoxic T cellsytotoksisuusPhysical and Theoretical ChemistryHomolepticCytotoxicityta116Cell ProliferationDose-Response Relationship DrugMolecular Structure010405 organic chemistryNitrosylationCombinatorial chemistry0104 chemical sciencesHEK293 Cellssyöpäsolutchemistrycancer cellsOvarian cancer cellscytotoxicityDrug Screening Assays AntitumorAzo CompoundsPalladiumPalladiumInorganic Chemistry
researchProduct

CCDC 1577120: Experimental Crystal Structure Determination

2018

Related Article: Alexander G. Tskhovrebov, Anna A. Vasileva, Richard Goddard, Tina Riedel, Paul J. Dyson, Vladimir N. Mikhaylov, Tatiyana V. Serebryanskaya, Viktor N. Sorokoumov, Matti Haukka|2018|Inorg.Chem.|57|930|doi:10.1021/acs.inorgchem.8b00072

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parametersbis{methyl 6-[(nitroso)amino]pyridine-3-carboxylatato}-palladium(ii)Experimental 3D Coordinates
researchProduct

CCDC 1577119: Experimental Crystal Structure Determination

2018

Related Article: Alexander G. Tskhovrebov, Anna A. Vasileva, Richard Goddard, Tina Riedel, Paul J. Dyson, Vladimir N. Mikhaylov, Tatiyana V. Serebryanskaya, Viktor N. Sorokoumov, Matti Haukka|2018|Inorg.Chem.|57|930|doi:10.1021/acs.inorgchem.8b00072

Space GroupCrystallographybis[5-methyl-N-(nitroso)pyridin-2-aminato]-palladium(ii)Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 1577118: Experimental Crystal Structure Determination

2018

Related Article: Alexander G. Tskhovrebov, Anna A. Vasileva, Richard Goddard, Tina Riedel, Paul J. Dyson, Vladimir N. Mikhaylov, Tatiyana V. Serebryanskaya, Viktor N. Sorokoumov, Matti Haukka|2018|Inorg.Chem.|57|930|doi:10.1021/acs.inorgchem.8b00072

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parametersbis[N-(nitroso)pyridin-2-aminato]-palladium(ii)Experimental 3D Coordinates
researchProduct

CCDC 1577121: Experimental Crystal Structure Determination

2018

Related Article: Alexander G. Tskhovrebov, Anna A. Vasileva, Richard Goddard, Tina Riedel, Paul J. Dyson, Vladimir N. Mikhaylov, Tatiyana V. Serebryanskaya, Viktor N. Sorokoumov, Matti Haukka|2018|Inorg.Chem.|57|930|doi:10.1021/acs.inorgchem.8b00072

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parametersbis{methyl 6-[(nitroso)amino]pyridine-3-carboxylatato}-palladium(ii)Experimental 3D Coordinates
researchProduct