0000000001301916

AUTHOR

Renè Hommelsheim

showing 9 related works from this author

A copper-catalyzed interrupted domino reaction for the synthesis of fused triazolyl benzothiadiazine-1-oxides

2023

Chemistry - a European journal 29(13), e202203729 (2023). doi:10.1002/chem.202203729

kemiallinen synteesikatalyysiddc:540Organic ChemistrykupariGeneral Chemistryheterosykliset yhdisteet540Catalysis
researchProduct

2-Sulfoximidoyl Acetic Acids from Multicomponent Petasis Reactions and Their Use as Building Blocks in Syntheses of Sulfoximine Benzodiazepine Analog…

2021

Upon application of a multicomponent Petasis reaction, a broad range of NH-sulfoximines and boronic acids react with glyoxalic acid to afford the corresponding 2-substituted acetic acids with N-bound sulfoximidoyl groups. The protocol features excellent yields under ambient, metal-free conditions and short reaction times. Furthermore, the applicability of 2-sulfoximidoyl acetic acids as building blocks for synthesizing sulfoximine-based benzodiazepine analogues was demonstrated.

BenzodiazepinePetasis reaction010405 organic chemistrymedicine.drug_classChemistryOrganic ChemistrymedicinePhysical and Theoretical Chemistry010402 general chemistry01 natural sciencesBiochemistryCombinatorial chemistry0104 chemical sciencesOrganic letters
researchProduct

CCDC 2169530: Experimental Crystal Structure Determination

2023

Related Article: Renè Hommelsheim, Sandra Bausch, Arjuna Selvakumar, Mostafa Amer, Khai-Nghi Truong, Kari Rissanen, Carsten Bolm|2023|Chem.-Eur.J.|29|e202203729|doi:10.1002/chem.202203729

Space GroupCrystallography1-azido-2-(S-methanesulfonimidoyl)benzeneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 2169531: Experimental Crystal Structure Determination

2023

Related Article: Renè Hommelsheim, Sandra Bausch, Arjuna Selvakumar, Mostafa Amer, Khai-Nghi Truong, Kari Rissanen, Carsten Bolm|2023|Chem.-Eur.J.|29|e202203729|doi:10.1002/chem.202203729

Space GroupCrystallography35-diphenyl-[123]triazolo[51-c][124]benzothiadiazin-5-oneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 2169543: Experimental Crystal Structure Determination

2023

Related Article: Renè Hommelsheim, Sandra Bausch, Arjuna Selvakumar, Mostafa Amer, Khai-Nghi Truong, Kari Rissanen, Carsten Bolm|2023|Chem.-Eur.J.|29|e202203729|doi:10.1002/chem.202203729

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters5-methyl-3-phenyl-[123]triazolo[51-c][124]benzothiadiazin-5-one dichloromethane solvateExperimental 3D Coordinates
researchProduct

CCDC 2169528: Experimental Crystal Structure Determination

2023

Related Article: Renè Hommelsheim, Sandra Bausch, Arjuna Selvakumar, Mostafa Amer, Khai-Nghi Truong, Kari Rissanen, Carsten Bolm|2023|Chem.-Eur.J.|29|e202203729|doi:10.1002/chem.202203729

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters3-phenyl-5-(trifluoromethyl)-[123]triazolo[51-c][124]benzothiadiazin-5-oneExperimental 3D Coordinates
researchProduct

CCDC 2169529: Experimental Crystal Structure Determination

2023

Related Article: Renè Hommelsheim, Sandra Bausch, Arjuna Selvakumar, Mostafa Amer, Khai-Nghi Truong, Kari Rissanen, Carsten Bolm|2023|Chem.-Eur.J.|29|e202203729|doi:10.1002/chem.202203729

5-methyl-3-phenyl-5a67899a-hexahydro-[123]triazolo[51-c][124]benzothiadiazin-5-one unknown solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 2169527: Experimental Crystal Structure Determination

2023

Related Article: Renè Hommelsheim, Sandra Bausch, Arjuna Selvakumar, Mostafa Amer, Khai-Nghi Truong, Kari Rissanen, Carsten Bolm|2023|Chem.-Eur.J.|29|e202203729|doi:10.1002/chem.202203729

Space GroupCrystallographyCrystal System5-methyl-3-phenyl-[123]triazolo[51-c][124]benzothiadiazin-5-one unknown solvateCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 2169532: Experimental Crystal Structure Determination

2023

Related Article: Renè Hommelsheim, Sandra Bausch, Arjuna Selvakumar, Mostafa Amer, Khai-Nghi Truong, Kari Rissanen, Carsten Bolm|2023|Chem.-Eur.J.|29|e202203729|doi:10.1002/chem.202203729

Space GroupCrystallography5-benzyl-3-phenyl-[123]triazolo[51-c][124]benzothiadiazin-5-oneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct