0000000001302894
AUTHOR
Pawel Jewula
A 4-tert-butylcalix[4]arene tetrahydroxamate podand based on the 1-oxypiperidine-2-one (1,2-PIPO−) chelate. Self-assembly into a supramolecular ionophore driven by coordination of tetravalent zirconium or hafnium(iv)
An octadentate tetrahydroxamic calix[4]arene podand incorporating 1-hydroxypiperidine-2-one (1,2-PIPOH) binding units has been designed as a specific chelator for tetravalent metal cations like Zr4+ or Hf4+. This receptor, which can be considered as the first ever abiotic ligand possessing only cyclic six-membered hydroxamate groups, has been synthesized and characterized in its tetraprotonated form (1H4). Contrary to expectation, however, this new chelator did not form a 1 : 1 complex upon reaction with M(acac)4 (M = Zr and Hf; acac = acetylacetonate), but rather self-assembled into a dimeric species of 2 : 2 stoichiometry. The latter could be characterized in solution by mass spectrometry…
Effects of preorganization in the chelation of UO22+ by hydroxamate ligands: cyclic PIPO– vs linear NMA–
International audience; Many siderophores incorporate as bidentate chelating subunits linear and more seldomly cyclic hydroxamate groups. In this work, a comparative study of the uranyl binding properties in aqueous solution of two monohydroxamic acids, the prototypical linear N-methylacetohydroxamic acid (NMAH) and the cyclic analog 1-hydroxypiperidine-2-one (PIPOH), has been carried out. The complex [UO2(PIPO)(2)(H2O)] crystallized from slightly acidic water solutions (pH < 5), and its molecular structure was determined by X-ray diffraction. The uranyl speciation in the presence of both ligands has been thoroughly investigated in a 0.1 M KNO3 medium at 298.2 K by the combined use of four …
Synthesis and Structural Study of Tetravalent (Zr 4+ , Hf 4+ , Ce 4+ , Th 4+ , U 4+ ) Metal Complexes with Cyclic Hydroxamic Acids
Six- and seven-membered cyclic hydroxamic acids, such as 1-hydroxypiperidine-2-one (1H, 1,2-PIPOH) and 1-hydroxyazepan-2-one (2H), have recently been identified in some mixed siderophores as one of their three chelating subunits. Compared to their ubiquitous noncyclic counterparts, cyclic hydroxamates are preorganized for metal binding. Surprisingly, the coordination chemistry of these bidentate, monoanionic ligands remains virtually unknown, even in the case of iron(III). We report herein the first structural study of the complexes of 1– and of 6–, an unsaturated seven-membered ring analog of 2–, with tetravalent cations of transition metals (zirconium and hafnium), lanthanide (cerium), an…
Designing Silylatedl-Amino Acids using a Wittig Strategy: Synthesis of Peptide Derivatives and18F-Labelling
An efficient semisynthesis of silylated l-amino acids by reaction of silylated benzaldehydes with a phosphonium l-amino acid used as a Wittig reagent is described. The efficiency of the silylated l-amino acids in peptide synthesis was investigated by coupling both the carboxylic acid and the amino moiety with l-alanine and phenylalanine derivatives, respectively. The silylated derivatives were treated with KF or tetrabutylammonium fluoride to give the corresponding fluorosilyl derivatives without racemization. The hydrolysis of the fluorosilylated derivatives in phosphate buffer at pH 7.2 was checked. Finally, the 18F-labelling of di-tert-butylsilylated saturated and unsaturated dipeptides …
CCDC 908612: Experimental Crystal Structure Determination
Related Article: Pawel Jewula, Jean-Claude Berthet, Jean-Claude Chambron, Yoann Rousselin, Pierre Thuéry, Michel Meyer|2015|Eur.J.Inorg.Chem.||1529|doi:10.1002/ejic.201403206
CCDC 908613: Experimental Crystal Structure Determination
Related Article: Pawel Jewula, Jean-Claude Berthet, Jean-Claude Chambron, Yoann Rousselin, Pierre Thuéry, Michel Meyer|2015|Eur.J.Inorg.Chem.||1529|doi:10.1002/ejic.201403206
CCDC 938729: Experimental Crystal Structure Determination
Related Article: Pawel Jewula, Jean-Claude Berthet, Jean-Claude Chambron, Yoann Rousselin, Pierre Thuéry, Michel Meyer|2015|Eur.J.Inorg.Chem.||1529|doi:10.1002/ejic.201403206
CCDC 983068: Experimental Crystal Structure Determination
Related Article: Pawel Jewula, Jean-Claude Chambron, Marie-José Penouilh, Yoann Rousselin, Michel Meyer|2014|RSC Advances|4|22743|doi:10.1039/C4RA00977K
CCDC 937567: Experimental Crystal Structure Determination
Related Article: Pawel Jewula, Jean-Claude Berthet, Jean-Claude Chambron, Yoann Rousselin, Pierre Thuéry, Michel Meyer|2015|Eur.J.Inorg.Chem.||1529|doi:10.1002/ejic.201403206
CCDC 937568: Experimental Crystal Structure Determination
Related Article: Pawel Jewula, Jean-Claude Berthet, Jean-Claude Chambron, Yoann Rousselin, Pierre Thuéry, Michel Meyer|2015|Eur.J.Inorg.Chem.||1529|doi:10.1002/ejic.201403206
CCDC 908614: Experimental Crystal Structure Determination
Related Article: Pawel Jewula, Jean-Claude Berthet, Jean-Claude Chambron, Yoann Rousselin, Pierre Thuéry, Michel Meyer|2015|Eur.J.Inorg.Chem.||1529|doi:10.1002/ejic.201403206
CCDC 1579042: Experimental Crystal Structure Determination
Related Article: Alejandra Sornosa-Ten, Pawel Jewula, Tamas Fodor, Stéphane Brandès, Vladimir Sladkov, Yoann Rousselin, Christine Stern, Jean-Claude Chambron, Michel Meyer|2018|New J.Chem.|42|7765|doi:10.1039/C8NJ00166A
CCDC 908617: Experimental Crystal Structure Determination
Related Article: Pawel Jewula, Jean-Claude Berthet, Jean-Claude Chambron, Yoann Rousselin, Pierre Thuéry, Michel Meyer|2015|Eur.J.Inorg.Chem.||1529|doi:10.1002/ejic.201403206
CCDC 937569: Experimental Crystal Structure Determination
Related Article: Pawel Jewula, Jean-Claude Berthet, Jean-Claude Chambron, Yoann Rousselin, Pierre Thuéry, Michel Meyer|2015|Eur.J.Inorg.Chem.||1529|doi:10.1002/ejic.201403206
CCDC 908616: Experimental Crystal Structure Determination
Related Article: Pawel Jewula, Jean-Claude Berthet, Jean-Claude Chambron, Yoann Rousselin, Pierre Thuéry, Michel Meyer|2015|Eur.J.Inorg.Chem.||1529|doi:10.1002/ejic.201403206
CCDC 908615: Experimental Crystal Structure Determination
Related Article: Pawel Jewula, Jean-Claude Berthet, Jean-Claude Chambron, Yoann Rousselin, Pierre Thuéry, Michel Meyer|2015|Eur.J.Inorg.Chem.||1529|doi:10.1002/ejic.201403206