0000000001302939
AUTHOR
Peter Heger
showing 10 related works from this author
Additional file 1: Figure S1. of Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects
2016
Tracing the evolutionary origin of CTCF with ancestral state reconstruction. Figure S2. Tracing the evolutionary origin of Su(Hw) with ancestral state reconstruction. Figure S3. Tracing the evolutionary origin of CP190 with ancestral state reconstruction. Figure S4. Tracing the evolutionary origin of GAF with ancestral state reconstruction. Figure S5. Tracing the evolutionary origin of Pita with ancestral state reconstruction. Figure S6. Tracing the evolutionary origin of Mod(mdg4) with ancestral state reconstruction. Figure S7. Tracing the evolutionary origin of Zw5 with ancestral state reconstruction. Figure S8. Phylogenetic gene tree of CTCF orthologs. Figure S9. Phylogenetic gene tree o…
Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects : Insect insulator proteins.
2016
Background Body plan development in multi-cellular organisms is largely determined by homeotic genes. Expression of homeotic genes, in turn, is partially regulated by insulator binding proteins (IBPs). While only a few enhancer blocking IBPs have been identified in vertebrates, the common fruit fly Drosophila melanogaster harbors at least twelve different enhancer blocking IBPs. We screened recently compiled insect transcriptomes from the 1KITE project and genomic and transcriptomic data from public databases, aiming to trace the origin of IBPs in insects and other arthropods. Results Our study shows that the last common ancestor of insects (Hexapoda) already possessed a substantial number …
Genome wide mapping of the MBF-1 binding sites during embryogenesis of the sea urchin reveals it is a chromatin organizer.
2015
The Zinc-finger MBF1 factor is a transcription activator involved in the expression of the early histone genes during development of the sea urchin embryo (1). The DNA-binding domain of MBF1 shares high sequence similarity with that of the CTCF chromatin organizer but, unexpectedly, extensive in silico analysis failed to identify the sea urchin CTCF ortholog (2, 3). This led us to speculate that MBF1 could have co-opted the function of CTCF during evolution of the echinoderms. To support this hypothesis, we performed the genome-wide MBF1-binding sites mapping in the P. lividus genome, by chromatin immunoprecipitation coupled to next generation sequencing (ChIP-Seq). We observed that MBF1 bi…
Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects
2016
BACKGROUND: Body plan development in multi-cellular organisms is largely determined by homeotic genes. Expression of homeotic genes, in turn, is partially regulated by insulator binding proteins (IBPs). While only a few enhancer blocking IBPs have been identified in vertebrates, the common fruit fly Drosophila melanogaster harbors at least twelve different enhancer blocking IBPs. We screened recently compiled insect transcriptomes from the 1KITE project and genomic and transcriptomic data from public databases, aiming to trace the origin of IBPs in insects and other arthropods. RESULTS: Our study shows that the last common ancestor of insects (Hexapoda) already possessed a substantial numbe…
Additional file 1: Figure S1. of Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects
2016
Tracing the evolutionary origin of CTCF with ancestral state reconstruction. Figure S2. Tracing the evolutionary origin of Su(Hw) with ancestral state reconstruction. Figure S3. Tracing the evolutionary origin of CP190 with ancestral state reconstruction. Figure S4. Tracing the evolutionary origin of GAF with ancestral state reconstruction. Figure S5. Tracing the evolutionary origin of Pita with ancestral state reconstruction. Figure S6. Tracing the evolutionary origin of Mod(mdg4) with ancestral state reconstruction. Figure S7. Tracing the evolutionary origin of Zw5 with ancestral state reconstruction. Figure S8. Phylogenetic gene tree of CTCF orthologs. Figure S9. Phylogenetic gene tree o…
Additional file 2: Table S1. of Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects
2016
BUSCO assessment of the 1KITE transcriptomes. (XLS 21 kb)
Additional file 3: Table S2. of Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects
2016
NCBI accession numbers of transcriptome and genome data. (XLS 35 kb)
Additional file 3: Table S2. of Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects
2016
NCBI accession numbers of transcriptome and genome data. (XLS 35 kb)
Data from: Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects
2017
Background Body plan development in multi-cellular organisms is largely determined by homeotic genes. Expression of homeotic genes, in turn, is partially regulated by insulator binding proteins (IBPs). While only a few enhancer blocking IBPs have been identified in vertebrates, the common fruit fly Drosophila melanogaster harbors at least twelve different enhancer blocking IBPs. We screened recently compiled insect transcriptomes from the 1KITE project and genomic and transcriptomic data from public databases, aiming to trace the origin of IBPs in insects and other arthropods. Results Our study shows that the last common ancestor of insects (Hexapoda) already possessed a substantial number …
Additional file 2: Table S1. of Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects
2016
BUSCO assessment of the 1KITE transcriptomes. (XLS 21 kb)