0000000001305099
AUTHOR
Alexandra R. Rivero
Synthesis of oxaspiranic compounds through [3 + 2] annulation of cyclopropenones and donor–acceptor cyclopropanes.
The Sc(OTf)3-catalyzed [3 + 2]-annulation reaction between cyclopropenones and donor–acceptor cyclopropanes is described. The process leads directly to the formation of 4-oxaspiro[2.4]hept-1-ene derivatives in good to excellent reaction yields. Density functional theory calculations suggest that the [3 + 2]-annulation pathway is strongly preferred over the possible [3 + 3]-process.
CCDC 1054408: Experimental Crystal Structure Determination
Related Article: Alexandra R. Rivero , Israel Fernández , Carmen Ramírez de Arellano , and Miguel A. Sierra|2015|J.Org.Chem.|80|1207|doi:10.1021/jo502292y