0000000001305304
AUTHOR
Christian Jandl
"Dynamical Docking" of Cyclic Dinuclear Au(I) Bis-N-heterocyclic Complexes Facilitates Their Binding to G-Quadruplexes.
With the aim to improve the design of metal complexes as stabilizers of noncanonical DNA secondary structures, namely, G-quadruplexes (G4s), a series of cyclic dinuclear Au(I) N-heterocyclic carbene complexes based on xanthine and benzimidazole ligands has been synthesized and characterized by various methods, including X-ray diffraction. Fluorescence resonance energy transfer (FRET) and CD DNA melting assays unraveled the compounds’ stabilization properties toward G4s of different topologies of physiological relevance. Initial structure–activity relationships have been identified and recognize the family of xanthine derivatives as those more selective toward G4s versus duplex DNA. The bind…
C−C Cross-Couplings from a Cyclometalated Au(III) C∧ N Complex: Mechanistic Insights and Synthetic Developments
Abstract In recent years, the reactivity of gold complexes was shown to extend well beyond π‐activation and to hold promises to achieve selective cross‐couplings in several C−C and C−E (E=heteroatom) bond forming reactions. Here, with the aim of exploiting new organometallic species for cross‐coupling reactions, we report on the Au(III)‐mediated C(sp2)−C(sp) occurring upon reaction of the cyclometalated complex [Au(CCH2N)Cl2] (1, CCH2N=2‐benzylpyridine) with AgPhCC. The reaction progress has been monitored by NMR spectroscopy, demonstrating the involvement of a number of key intermediates, whose structures have been unambiguously ascertained through 1D and 2D NMR analyses (1H, 13C, 1H‐1H CO…
CCDC 2202919: Experimental Crystal Structure Determination
Related Article: Clemens Kaußler, Darren Wragg, Claudia Schmidt, Guillermo Moreno-Alcántar, Christian Jandl, Johannes Stephan, Roland A. Fischer, Stefano Leoni, Angela Casini, Riccardo Bonsignore|2022|Inorg.Chem.|61|20405|doi:10.1021/acs.inorgchem.2c03041
CCDC 2082255: Experimental Crystal Structure Determination
Related Article: Riccardo Bonsignore, Sophie R. Thomas, Mathilde Rigoulet, Christian Jandl, Alexander P��thig, Didier Bourissou, Giampaolo Barone, Angela Casini|2021|Chem.-Eur.J.|27|14322|doi:10.1002/chem.202102668
CCDC 2082254: Experimental Crystal Structure Determination
Related Article: Riccardo Bonsignore, Sophie R. Thomas, Mathilde Rigoulet, Christian Jandl, Alexander Pöthig, Didier Bourissou, Giampaolo Barone, Angela Casini|2021|Chem.-Eur.J.|27|14322|doi:10.1002/chem.202102668
CCDC 2202918: Experimental Crystal Structure Determination
Related Article: Clemens Kaußler, Darren Wragg, Claudia Schmidt, Guillermo Moreno-Alcántar, Christian Jandl, Johannes Stephan, Roland A. Fischer, Stefano Leoni, Angela Casini, Riccardo Bonsignore|2022|Inorg.Chem.|61|20405|doi:10.1021/acs.inorgchem.2c03041
CCDC 2202916: Experimental Crystal Structure Determination
Related Article: Clemens Kaußler, Darren Wragg, Claudia Schmidt, Guillermo Moreno-Alcántar, Christian Jandl, Johannes Stephan, Roland A. Fischer, Stefano Leoni, Angela Casini, Riccardo Bonsignore|2022|Inorg.Chem.|61|20405|doi:10.1021/acs.inorgchem.2c03041
CCDC 2082253: Experimental Crystal Structure Determination
Related Article: Riccardo Bonsignore, Sophie R. Thomas, Mathilde Rigoulet, Christian Jandl, Alexander Pöthig, Didier Bourissou, Giampaolo Barone, Angela Casini|2021|Chem.-Eur.J.|27|14322|doi:10.1002/chem.202102668
CCDC 2202920: Experimental Crystal Structure Determination
Related Article: Clemens Kaußler, Darren Wragg, Claudia Schmidt, Guillermo Moreno-Alcántar, Christian Jandl, Johannes Stephan, Roland A. Fischer, Stefano Leoni, Angela Casini, Riccardo Bonsignore|2022|Inorg.Chem.|61|20405|doi:10.1021/acs.inorgchem.2c03041
CCDC 2096758: Experimental Crystal Structure Determination
Related Article: Riccardo Bonsignore, Sophie R. Thomas, Mathilde Rigoulet, Christian Jandl, Alexander Pöthig, Didier Bourissou, Giampaolo Barone, Angela Casini|2021|Chem.-Eur.J.|27|14322|doi:10.1002/chem.202102668
CCDC 2202917: Experimental Crystal Structure Determination
Related Article: Clemens Kaußler, Darren Wragg, Claudia Schmidt, Guillermo Moreno-Alcántar, Christian Jandl, Johannes Stephan, Roland A. Fischer, Stefano Leoni, Angela Casini, Riccardo Bonsignore|2022|Inorg.Chem.|61|20405|doi:10.1021/acs.inorgchem.2c03041