0000000001306829

AUTHOR

A. Sunil Kumar

showing 4 related works from this author

Synthesis, characterization, crystal structures and biological screening of 4-amino quinazoline sulfonamide derivatives

2019

Three quinazolin-4-ylamino derivatives containing phenylbenzenesulfonamides (7a-7c) were synthesized by reacting (E)-N'-(2-cyanophenyl)-N,N-dimethyl formamidine (6) with different 4- amino-N-(phenyl)benzenesulfonamides (4a-4c) and characterized by different techniques such as HRMS, IR, 1H NMR and 13C NMR spectroscopy. The structural properties were further examined by single crystal X-ray diffraction method. The X-ray data shows that compounds 7a and 7c contain two molecules and 7b contains one molecule in the asymmetric unit. Comparison of conformation of two distinct molecules, “A” and “B”, in the asymmetric unit of 7a and 7c were studied with the aid of reported literature. The in vitro …

antiproliferative activitycrystal structurearomaattiset yhdisteetStereochemistryX-ray-diffractionCrystal structure010402 general chemistry01 natural sciencesAnalytical ChemistryInorganic Chemistrychemistry.chemical_compoundQuinazolineMoleculeta116Spectroscopychemistry.chemical_classificationantimikrobiset yhdisteetkemiallinen synteesi010405 organic chemistryOrganic Chemistryta1182Antimicrobialquinazoline-sulfonamide0104 chemical sciencesSulfonamidechemistryX-ray crystallographysolunsalpaajatProton NMRantimicrobialSingle crystal
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CCDC 1563909: Experimental Crystal Structure Determination

2019

Related Article: A. Sunil Kumar, Jyothi Kudva, B. R. Bharath, Vaishali M Rai, S. Madan Kumar, Vasantha Kumar, Shyama Prasad Sajankila|2018|Chem. Sel.|3|13586|doi:10.1002/slct.201802402

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersN-(4-fluorophenyl)-4-[(quinazolin-4-yl)amino]benzene-1-sulfonamideExperimental 3D Coordinates
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CCDC 1857204: Experimental Crystal Structure Determination

2019

Related Article: A. Sunil Kumar, Jyothi Kudva, Manu Lahtinern, Anssi Peuronen, Rajitha Sadashiva, Damodara Naral|2019|J.Mol.Struct.|1190|29|doi:10.1016/j.molstruc.2019.04.050

N-(4-methylphenyl)-4-[(quinazolin-4-yl)amino]benzene-1-sulfonamideSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1857205: Experimental Crystal Structure Determination

2019

Related Article: A. Sunil Kumar, Jyothi Kudva, Manu Lahtinern, Anssi Peuronen, Rajitha Sadashiva, Damodara Naral|2019|J.Mol.Struct.|1190|29|doi:10.1016/j.molstruc.2019.04.050

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersN-(4-chlorophenyl)-4-[(quinazolin-4-yl)amino]benzene-1-sulfonamideExperimental 3D Coordinates
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