0000000001307259
AUTHOR
Mohamed El Haimer
showing 5 related works from this author
Synthesis and biological evaluation of the new ring system benzo[f]pyrimido[1,2-d][1,2,3]triazolo[1,5-a][1,4]diazepine and its cycloalkane and cycloa…
2021
Derivatives of the new ring system benzo[f]pyrimido[1,2-d][1,2,3]triazolo[1,5-a][1,4]diazepinone and its cycloalkane and cycloalkene condensed analogues have been conveniently synthesized through a three-step reaction sequence. An atom-economical, one-pot, three-step cascade process engaging five reactive centers (amide, amine, carbonyl, azide, and alkyne) has been performed for the synthesis of alicyclic derivatives of quinazolinotriazolobenzodiazepine using cyclohexane, cyclohexene, and norbornene β-amino amides. The stereochemistry and relative configurations of the synthesized compounds were determined by 1D and 2D NMR spectroscopy and X-ray crystallography. The reaction was also perfor…
Synthesis and biological evaluation of the new ring system benzo[f]pyrimido[1,2-d][1,2,3]triazolo[1,5-a][1,4]diazepine and its cycloalkane and cycloa…
2021
Derivatives of the new ring system benzo[f]pyrimido[1,2-d][1,2,3]triazolo[1,5-a][1,4]diazepinone and its cycloalkane and cycloalkene condensed analogues have been conveniently synthesized through a three-step reaction sequence. An atom-economical, one-pot, three-step cascade process engaging five reactive centers (amide, amine, carbonyl, azide, and alkyne) has been performed for the synthesis of alicyclic derivatives of quinazolinotriazolobenzodiazepine using cyclohexane, cyclohexene, and norbornene β-amino amides. The stereochemistry and relative configurations of the synthesized compounds were determined by 1D and 2D NMR spectroscopy and X-ray crystallography. The reaction was also perfor…
CCDC 2048904: Experimental Crystal Structure Determination
2021
Related Article: Mohamed El Haimer, Márta Palkó, Matti Haukka, Márió Gajdács, István Zupkó, Ferenc Fülöp|2021|RSC Advances|11|6952|doi:10.1039/D0RA10553H
CCDC 2048905: Experimental Crystal Structure Determination
2021
Related Article: Mohamed El Haimer, Márta Palkó, Matti Haukka, Márió Gajdács, István Zupkó, Ferenc Fülöp|2021|RSC Advances|11|6952|doi:10.1039/D0RA10553H
CCDC 2048906: Experimental Crystal Structure Determination
2021
Related Article: Mohamed El Haimer, Márta Palkó, Matti Haukka, Márió Gajdács, István Zupkó, Ferenc Fülöp|2021|RSC Advances|11|6952|doi:10.1039/D0RA10553H