0000000001307846

AUTHOR

Patrícia Fernandes

Fluoroquinolone–metal complexes: A route to counteract bacterial resistance?

Abstract Microbial resistance to antibiotics is one of the biggest public health threats of the modern world. Antibiotic resistance is an area of much clinical relevance and therefore research that has the potential to identify agents that may circumvent it or treat resistant infections is paramount. Solution behavior of various fluoroquinolone (FQ) complexes with copper(II) in the presence and absence of 1,10-phenanthroline (phen) was studied in aqueous solution, by potentiometry and/or spectrophotometry, and are herein described. The results obtained showed that under physiological conditions (micromolar concentration range and pH 7.4) only copper(II):FQ:phen ternary complexes are stable.…

research product

Relationship between recruitment and mother plant vitality in the alien species Acacia cyclops A. Cunn. ex G. Don

Acacia cyclops is a widespread invader in Mediterranean-climate regions. However, although its naturalization in the Mediterranean Basin dates back only a few years ago, and the invasion process has not been studied hitherto. We investigated seedlings recruitment strategy adopted by A. cyclops in a small island (Lampedusa, Italy) where its natural regeneration was strictly confined under mother plants canopy. Healthy plants (DCP), plants at incipient senescence (SCP) and dead plants (DP) were distinguished according to vitality and canopy status. Living plants were also characterized in relation to leaf C and N isotope composition. Regeneration pattern (seedlings and saplings abundance) was…

research product

CCDC 990231: Experimental Crystal Structure Determination

Related Article: Maria J. Feio, Isabel Sousa, Mariana Ferreira, Luís Cunha-Silva, Raúl G. Saraiva, Carla Queirós, José G. Alexandre, Vasco Claroa, AdéliaMendes, RosaOrtiz, Sandra Lopes, Ana Luísa Amaral, João Lino, Patrícia Fernandes, Ana João Silva, Lisete Moutinho, Baltazar de Castro, Eulália Pereira, Lourdes Perelló, Paula Gameiro|2014|J.Inorg.Biochem.|138|129|doi:10.1016/j.jinorgbio.2014.05.007

research product

CCDC 990233: Experimental Crystal Structure Determination

Related Article: Maria J. Feio, Isabel Sousa, Mariana Ferreira, Luís Cunha-Silva, Raúl G. Saraiva, Carla Queirós, José G. Alexandre, Vasco Claroa, AdéliaMendes, RosaOrtiz, Sandra Lopes, Ana Luísa Amaral, João Lino, Patrícia Fernandes, Ana João Silva, Lisete Moutinho, Baltazar de Castro, Eulália Pereira, Lourdes Perelló, Paula Gameiro|2014|J.Inorg.Biochem.|138|129|doi:10.1016/j.jinorgbio.2014.05.007

research product