0000000001308124

AUTHOR

Hanna Jędrzejewska

showing 4 related works from this author

Dynamic formation of hybrid peptidic capsules by chiral self-sorting and self-assembly.

2014

Owing to their versatility and biocompatibility, peptide-based self-assembled structures constitute valuable targets for complex functional designs. It is now shown that artificial capsules based on β-barrel binding motifs can be obtained by means of dynamic covalent chemistry (DCC) and self-assembly. Short peptides (up to tetrapeptides) are reversibly attached to resorcinarene scaffolds. Peptidic capsules are thus selectively formed in either a heterochiral or a homochiral way by simultaneous and spontaneous processes, involving chiral sorting, tautomerization, diastereoselective induction of inherent chirality, and chiral self-assembly. Self-assembly is shown to direct the regioselectivit…

ChemistryStereochemistryProton Magnetic Resonance SpectroscopySupramolecular chemistryDynamic covalent chemistryRegioselectivityStereoisomerismGeneral ChemistryGeneral MedicineResorcinareneInherent chiralityTautomerCatalysisSelf-assemblyChirality (chemistry)Peptidesta116Angewandte Chemie (International ed. in English)
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CCDC 1006725: Experimental Crystal Structure Determination

2014

Related Article: Hanna Jędrzejewska, Michał Wierzbicki, Piotr Cmoch, Kari Rissanen, Agnieszka Szumna|2014|Angew.Chem.,Int.Ed.|53|13760|doi:10.1002/anie.201407802

Space GroupCrystallographyCrystal System(D)-2-benzyl-2-[(([benzyl(([111723-tris(39-dichloro-4710-trioxo-25811-tetraazadodec-1-ylidene)-4101622-tetrahydroxy-281420-tetrakis(2-methylpropyl)-6121824-tetraoxopentacyclo[19.3.1.137.1913.11519]octacosa-1(25)37(28)913(27)1519(26)21-octaen-5-ylidene]methyl)amino)acetyl]amino)acetyl)amino]-N-methylacetamide (L)-2-benzyl-2-[(([benzyl(([111723-tris(39-dichloro-4710-trioxo-25811-tetraazadodec-1-ylidene)-4101622-tetrahydroxy-281420-tetrakis(2-methylpropyl)-6121824-tetraoxopentacyclo[19.3.1.137.1913.11519]octacosa-1(25)37(28)913(27)1519(26)21-octaen-5-ylidene]methyl)amino)acetyl]amino)acetyl)amino]-N-methylacetamide cyclohexane solvateCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1006724: Experimental Crystal Structure Determination

2014

Related Article: Hanna Jędrzejewska, Michał Wierzbicki, Piotr Cmoch, Kari Rissanen, Agnieszka Szumna|2014|Angew.Chem.,Int.Ed.|53|13760|doi:10.1002/anie.201407802

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(D/L)-6121824-Tetrahydroxy-281420-tetraisobutyl-5111723-tetrakis(((1-(methylamino)-1-oxo-3-phenylpropan-2-yl)iminio)methyl)calix(4)arene-4101622-tetrolate toluene solvateExperimental 3D Coordinates
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CCDC 1006726: Experimental Crystal Structure Determination

2014

Related Article: Hanna Jędrzejewska, Michał Wierzbicki, Piotr Cmoch, Kari Rissanen, Agnieszka Szumna|2014|Angew.Chem.,Int.Ed.|53|13760|doi:10.1002/anie.201407802

Space GroupCrystallographyCrystal System(D)-6121824-Tetrahydroxy-281420-tetraisobutyl-5111723-tetrakis(((1-((2-(methylamino)-2-oxoethyl)amino)-1-oxo-3-phenylpropan-2-yl)iminio)methyl)calix(4)arene-4101622-tetrolate (D)-46101216182224-octahydroxy-281420-tetraisobutyl-5111723-tetrakis(((1-((2-(methylamino)-2-oxoethyl)amino)-1-oxo-3-phenylpropan-2-yl)imino)methyl)calix(4)arene chloroform methanol solvateCrystal StructureCell ParametersExperimental 3D Coordinates
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