0000000001308623
AUTHOR
Samir Hamamah
Additional file 1: Table S1. of Apolipoprotein B is regulated by gonadotropins and constitutes a predictive biomarker of IVF outcomes
Patients' characteristics. All values are reported by the mean ± SD (Standard Deviation) or the number of subjects (percentage of the total). BMI, Body Mass Index; IVF, In Vitro Fertilization; ICSI, Intracytoplasmic Sperm Injection. (DOCX 12 kb)
Additional file 2: Table S2. of Apolipoprotein B is regulated by gonadotropins and constitutes a predictive biomarker of IVF outcomes
Description of patients' characteristics according to APOB concentrations divided into quartiles. Q1, quartile 1; Q2, quartile 2; Q3, quartile 3; Q4, quartile 4; SD, Standard Deviation; CI, Confidence Intervals, BMI, Body Mass Index; IVF, In Vitro Fertilization; ICSI, Intracytoplasmic Sperm Injection. (DOCX 15Â kb)
Male infertility: an obstacle to sexuality?
International audience; Interactions between infertility and sexuality are numerous and complex. Infertile men may suffer from sexual dysfunction (SD) when undergoing an assisted reproductive technology programme. We undertook a review both in French and English of the available data on male SD when being diagnosed with a fertility problem with a specific focus on azoospermic men. The review was performed over a 30-year time period using PubMed/Medline. The sexual concerns and needs of infertile/sterile men for whom potential parenting can be compromised were evaluated. When diagnosed with infertility, men usually go through a crisis that can have a deleterious effect on their sexuality wit…
Apolipoprotein B is regulated by gonadotropins and constitutes a predictive biomarker of IVF outcomes
Background Follicular fluid (FF) is an important micro-environment influencing oocyte growth, its development competence, and embryo viability. The FF content analysis allows to identify new relevant biomarkers, which could be predictive of in vitro fertilization (IVF) outcomes. Inside ovarian follicle, the amount of FF components from granulosa cells (GC) secretion, could be regulated by gonadotropins, which play a major role in follicle development. Methods This prospective study included 61 female undergoing IVF or Intra-cytoplasmic sperm injection (ICSI) procedure. Apolipoprotein B (APOB) concentrations in follicular fluid and APOB gene and protein expression in granulosa cells from rep…
Additional file 3: Figure S1. of Apolipoprotein B is regulated by gonadotropins and constitutes a predictive biomarker of IVF outcomes
17 β-estradiol quantification (ng/l) into culture medium by immuno-chemiluminescence. Androstenedione (And) was added to the culture medium to provide specific substrate to granulosa cells, for oestrogen synthesis. (TIF 69 kb)
Additional file 3: Figure S1. of Apolipoprotein B is regulated by gonadotropins and constitutes a predictive biomarker of IVF outcomes
17 β-estradiol quantification (ng/l) into culture medium by immuno-chemiluminescence. Androstenedione (And) was added to the culture medium to provide specific substrate to granulosa cells, for oestrogen synthesis. (TIF 69 kb)
Additional file 4: Figure S2. of Apolipoprotein B is regulated by gonadotropins and constitutes a predictive biomarker of IVF outcomes
The constant GAPDH gene expression in GC pools (n = 10) under our experiment conditions. All Ct-values were reported for the different GC pools from FF samples. (JPG 137 kb)
Additional file 4: Figure S2. of Apolipoprotein B is regulated by gonadotropins and constitutes a predictive biomarker of IVF outcomes
The constant GAPDH gene expression in GC pools (n = 10) under our experiment conditions. All Ct-values were reported for the different GC pools from FF samples. (JPG 137 kb)