0000000001311042
AUTHOR
Adrian V. Hauck
showing 3 related works from this author
Electrochemical Synthesis of Fluorinated Orthoesters from 1,3‐Benzodioxoles
2019
Abstract Invited for this month's cover picture is the group of Professor Siegfried Waldvogel. The cover picture displays the robustness achieved by the installation of fluorinated alcohols on 1,3‐benzodioxoles, protecting the obtained orthoesters against acids and bases, like the shield of a knight. The simple protocol allows access to interesting compounds, whose lipophilicity is tremendously increased by the incorporation of fluorinated groups. This makes it possible to adjust the physicochemical properties of the biologically active 1,3‐benzodioxole motif. The surprisingly high stability against acids and bases gives rise to subsequent functionalizations or direct application in medicin…
Front Cover: Electrochemical Synthesis of Fluorinated Orthoesters from 1,3‐Benzodioxoles (ChemistryOpen 9/2019)
2019
The Front Cover shows the robustness achieved by the installation of fluorinated alcohols on 1,3‐benzodioxoles, which appears like the shield of a knight protecting the obtained orthoesters against acids and bases. The simple protocol allows access to interesting compounds, whose lipophilicity is tremendously increased by the incorporation of fluorinated groups. This makes it possible to adjust the physicochemical properties of the biologically active 1,3‐benzodioxole motif. The surprisingly high stability against acids and bases gives rise to subsequent functionalizations or direct application in medicinal or agrochemistry. More information can be found in the Communication by J. L. Röckl …
CCDC 1903303: Experimental Crystal Structure Determination
2020
Related Article: Johannes L. Röckl, Adrian V. Hauck, Dieter Schollmeyer, Siegfried R. Waldvogel|2019|ChemistryOpen|8|1167|doi:10.1002/open.201900127