0000000001311312
AUTHOR
Peter James
showing 7 related works from this author
Impact of diet-induced obesity on the mouse brain phosphoproteome
2018
Obesity is closely associated to several diseases such as type 2 diabetes, cardiovascular disease, hepatic steatosis, airway disease, neurodegeneration, biliary diseases and certain cancers. It is, therefore, of importance to assess the role of nutrition in disease prevention as well as its effect in the course of such pathologies. In the present study, we addressed the impact of the exposure to different obesogenic diets in the mice brains phosphoproteome. To analyze if the obesity could be able to modify the protein pattern expression of brain neurons, obesity was induced in two different groups of mice. One group of mice was fed with hyperglycemic diet (HGD) and the other one was fed wit…
Polypeptide sequence of the chlorophyll a/b/c-binding protein of the prasinophycean alga Mantoniella squamata.
1994
The primary structure of the Chla/b/c-binding protein from Mantoniella squamata is determined. This is the first report that protein sequencing reveals one modified amino acid resulting in a LHCP-specific TFA-cleavage site. The comparison of the sequence of Mantoniella with other Chla/b-and Chla/c-binding proteins shows that the modified amino acid is located in a region which is highly conserved in all these proteins. The alignment also reveals that the LHCP of Mantoniella is related to the Chla/b-binding proteins. Finally, possible Chl-binding regions are discussed.
Obesogenic Diets Cause Alterations on Proteins and Theirs Post-Translational Modifications in Mouse Brains
2021
Obesity constitutes a major global health threat and is associated with a variety of diseases ranging from metabolic and cardiovascular disease, cancer to neurodegeneration. The hallmarks of neurodegeneration include oxidative stress, proteasome impairment, mitochondrial dysfunction and accumulation of abnormal protein aggregates as well as metabolic alterations. As an example, in post-mortem brain of patients with Alzheimer’s disease (AD), several studies have reported reduction of insulin, insulin-like growth factor 1 and insulin receptor and an increase in tau protein and glycogen-synthase kinase-3β compared to healthy controls suggesting an impairment of metabolism in the AD patient’s …
sj-docx-1-nmi-10.1177_11786388211012405 – Supplemental material for Obesogenic Diets Cause Alterations on Proteins and Theirs Post-Translational Modi…
2021
Supplemental material, sj-docx-1-nmi-10.1177_11786388211012405 for Obesogenic Diets Cause Alterations on Proteins and Theirs Post-Translational Modifications in Mouse Brains by Valentina Siino, Pia Jensen, Peter James, Sonya Vasto, Antonella Amato, Flavia è, Giulia Accardi and Martin Røssel Larsen in Nutrition and Metabolic Insights
sj-docx-1-nmi-10.1177_11786388211012405 – Supplemental material for Obesogenic Diets Cause Alterations on Proteins and Theirs Post-Translational Modi…
2021
Supplemental material, sj-docx-1-nmi-10.1177_11786388211012405 for Obesogenic Diets Cause Alterations on Proteins and Theirs Post-Translational Modifications in Mouse Brains by Valentina Siino, Pia Jensen, Peter James, Sonya Vasto, Antonella Amato, Flavia è, Giulia Accardi and Martin Røssel Larsen in Nutrition and Metabolic Insights
sj-xlsx-2-nmi-10.1177_11786388211012405 – Supplemental material for Obesogenic Diets Cause Alterations on Proteins and Theirs Post-Translational Modi…
2021
Supplemental material, sj-xlsx-2-nmi-10.1177_11786388211012405 for Obesogenic Diets Cause Alterations on Proteins and Theirs Post-Translational Modifications in Mouse Brains by Valentina Siino, Pia Jensen, Peter James, Sonya Vasto, Antonella Amato, Flavia è, Giulia Accardi and Martin Røssel Larsen in Nutrition and Metabolic Insights
sj-xlsx-3-nmi-10.1177_11786388211012405 – Supplemental material for Obesogenic Diets Cause Alterations on Proteins and Theirs Post-Translational Modi…
2021
Supplemental material, sj-xlsx-3-nmi-10.1177_11786388211012405 for Obesogenic Diets Cause Alterations on Proteins and Theirs Post-Translational Modifications in Mouse Brains by Valentina Siino, Pia Jensen, Peter James, Sonya Vasto, Antonella Amato, Flavia è, Giulia Accardi and Martin Røssel Larsen in Nutrition and Metabolic Insights