0000000001311985

AUTHOR

Lucia Quintero

showing 2 related works from this author

Organocatalytic Enantioselective Synthesis of α-Hydroxyketones through a Friedel−Crafts Reaction of Naphthols and Activated Phenols with Aryl- and Al…

2016

[EN] An efficient organocatalytic asymmetric synthesis of alpha-hydroxyketones has been developed. Quinine-derived thiourea catalyzed the enantioselective Friedel Crafts alkylation of naphthols and activated phenols with aryl- and alkylglyoxal hydrates, providing the corresponding chiral alpha-hydroxyketones with high yields (up to 97%) and excellent enantioselectivities (up to 99% ee).

Intramolecular Cannizzaro reactionOne-pot synthesisAlkylation010402 general chemistry01 natural sciencesBiochemistryCatalysisReaccions químiqueschemistry.chemical_compound(R)-Alpha-Hydroxy ketonesCatàlisiCinchona alkaloidsHighly efficientStereoselective-SynthesisOrganic chemistryPhenolsPhysical and Theoretical ChemistryFriedel–Crafts reactionDynamic kinetic resolutionElectron-Rich phenols010405 organic chemistryArylOrganic ChemistryEnantioselective synthesisOne-Pot synthesis0104 chemical scienceschemistryThioureaCarbonyl-CompoundsFISICA APLICADAAsymmetric benzoin condensationQuímica orgànica
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CCDC 1505242: Experimental Crystal Structure Determination

2016

Related Article: Carlos Vila, Lucia Quintero, Gonzalo Blay, M. Carmen Muñoz, José R. Pedro|2016|Org.Lett.|18|5652|doi:10.1021/acs.orglett.6b02893

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters2-hydroxy-2-(1-hydroxy-2-naphthyl)-1-(2-thienyl)ethanoneExperimental 3D Coordinates
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