0000000001312042
AUTHOR
Laurent Bonneviot
A top-down synthesis route to ultrasmall multifunctional Gd-based Silica nanoparticles for theranostic applications
International audience; New, ultrasmall nanoparticles with sizes below 5 nm have been obtained. These small rigid platforms (SRP) are composed of a polysiloxane matrix with DOTAGA (1,4,7,10-tetraazacyclododecane-1-glutaric anhydride-4,7,10-triacetic acid)-Gd3+ chelates on their surface. They have been synthesised by an original top-down process: 1) formation of a gadolinium oxide Gd2O3 core, 2) encapsulation in a polysiloxane shell grafted with DOTAGA ligands, 3) dissolution of the gadolinium oxide core due to chelation of Gd3+ by DOTAGA ligands and 4) polysiloxane fragmentation. These nanoparticles have been fully characterised using photon correlation spectroscopy (PCS), transmission elec…
Biomimetic Mn-catalases based on dimeric manganese complexes in mesoporous silica for potential antioxidant agent
Two new structural and functional models of the Mn-catalase with formula [{Mn(III)(bpy)(H2O)}(μ-2-MeOC6H4CO2)2(μ-O){Mn(III)(bpy)(X)}]X, where X = NO3 (1) and ClO4 (2) and bpy = 2,2'-bipyridine, were synthesized and characterized by X-ray diffraction. In both cases, a water molecule and an X ion occupy the monodentate positions. The magnetic properties of these compounds reveal a weak antiferromagnetic behavior (2J = -2.2 cm(-1) for 1 and -0.7 cm(-1) for 2, using the spin Hamiltonian H = -2J S1·S2) and negative zero-field splitting parameter DMn (-4.6 cm(-1) and -3.0 cm(-1) for 1 and 2, respectively). This fact, together with the nearly orthogonal orientation of the Jahn-Teller axes of the M…
Bioinspired manganese(II) complexes with a clickable ligand for immobilisation on a solid support.
International audience; Clickable ligands like N,N′-bis((pyridin-2-yl)methyl)prop-2-yn-1-amine (L1) and N-((1-methyl-1H-imidazol-2-yl)methyl)-N-(pyridin-2-ylmethyl)prop-2-yn-1-amine (L2) have been used to synthesise a series of manganese(II) complexes for grafting onto appropriate solid supports. These ligands mimic the 2-His-1-carboxylate facial chelation present in the active site of the manganese-dependent dioxygenase (MndD), while the alkyne side function allows grafting of the ligand onto an azido-functionalised support using “click chemistry” methodologies. Such synthetic analogues of the MndD crystallise in the solid state as double halide or pseudohalide-bridged dinuclear manganese(…
CCDC 911104: Experimental Crystal Structure Determination
Related Article: Jérémy Chaignon, Salah-Eddine Stiriba, Francisco Lloret, Consuelo Yuste, Guillaume Pilet, Laurent Bonneviot, Belén Albela, Isabel Castro|2014|Dalton Trans.|43|9704|doi:10.1039/C3DT53636J
CCDC 911105: Experimental Crystal Structure Determination
Related Article: Jérémy Chaignon, Salah-Eddine Stiriba, Francisco Lloret, Consuelo Yuste, Guillaume Pilet, Laurent Bonneviot, Belén Albela, Isabel Castro|2014|Dalton Trans.|43|9704|doi:10.1039/C3DT53636J
CCDC 1040032: Experimental Crystal Structure Determination
Related Article: Luis Escriche-Tur, Montserrat Corbella, Mercè Font-Bardia, Isabel Castro, Laurent Bonneviot, and Belén Albela|2015|Inorg.Chem.|54|10111|doi:10.1021/acs.inorgchem.5b01425
CCDC 911106: Experimental Crystal Structure Determination
Related Article: Jérémy Chaignon, Salah-Eddine Stiriba, Francisco Lloret, Consuelo Yuste, Guillaume Pilet, Laurent Bonneviot, Belén Albela, Isabel Castro|2014|Dalton Trans.|43|9704|doi:10.1039/C3DT53636J
CCDC 905065: Experimental Crystal Structure Determination
Related Article: Jérémy Chaignon, Salah-Eddine Stiriba, Francisco Lloret, Consuelo Yuste, Guillaume Pilet, Laurent Bonneviot, Belén Albela, Isabel Castro|2014|Dalton Trans.|43|9704|doi:10.1039/C3DT53636J
CCDC 1040033: Experimental Crystal Structure Determination
Related Article: Luis Escriche-Tur, Montserrat Corbella, Mercè Font-Bardia, Isabel Castro, Laurent Bonneviot, and Belén Albela|2015|Inorg.Chem.|54|10111|doi:10.1021/acs.inorgchem.5b01425