Author: Belén Albela

0000000001312043

AUTHOR

Belén Albela

showing 9 related works from this author

A top-down synthesis route to ultrasmall multifunctional Gd-based Silica nanoparticles for theranostic applications

2013

International audience; New, ultrasmall nanoparticles with sizes below 5 nm have been obtained. These small rigid platforms (SRP) are composed of a polysiloxane matrix with DOTAGA (1,4,7,10-tetraazacyclododecane-1-glutaric anhydride-4,7,10-triacetic acid)-Gd3+ chelates on their surface. They have been synthesised by an original top-down process: 1) formation of a gadolinium oxide Gd2O3 core, 2) encapsulation in a polysiloxane shell grafted with DOTAGA ligands, 3) dissolution of the gadolinium oxide core due to chelation of Gd3+ by DOTAGA ligands and 4) polysiloxane fragmentation. These nanoparticles have been fully characterised using photon correlation spectroscopy (PCS), transmission elec…

Magnetic Resonance SpectroscopySiloxanesGadoliniumtheranosticAnalytical chemistryContrast Mediachemistry.chemical_elementNanoparticle02 engineering and technologySubstance P010402 general chemistry01 natural sciencesCatalysisFluorescence spectroscopylaw.inventionHeterocyclic Compounds 1-RingMicroscopy Electron TransmissionDynamic light scatteringlawcancer[CHIM]Chemical SciencesChelationSpectroscopyElectron paramagnetic resonanceOrganic ChemistryGeneral ChemistryNuclear magnetic resonance spectroscopySilicon Dioxide021001 nanoscience & nanotechnologyMagnetic Resonance Imaging0104 chemical sciencesSpectrometry Fluorescencechemistrysilicananoparticlesgadolinium0210 nano-technologyRadiotherapy Image-GuidedNuclear chemistry

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Biomimetic Mn-catalases based on dimeric manganese complexes in mesoporous silica for potential antioxidant agent

2015

Two new structural and functional models of the Mn-catalase with formula [{Mn(III)(bpy)(H2O)}(μ-2-MeOC6H4CO2)2(μ-O){Mn(III)(bpy)(X)}]X, where X = NO3 (1) and ClO4 (2) and bpy = 2,2'-bipyridine, were synthesized and characterized by X-ray diffraction. In both cases, a water molecule and an X ion occupy the monodentate positions. The magnetic properties of these compounds reveal a weak antiferromagnetic behavior (2J = -2.2 cm(-1) for 1 and -0.7 cm(-1) for 2, using the spin Hamiltonian H = -2J S1·S2) and negative zero-field splitting parameter DMn (-4.6 cm(-1) and -3.0 cm(-1) for 1 and 2, respectively). This fact, together with the nearly orthogonal orientation of the Jahn-Teller axes of the M…

DenticitySilicon dioxideInorganic chemistrychemistry.chemical_elementManganeseCrystallography X-Ray010402 general chemistryLigands01 natural sciencesAntioxidantsCoordination complexBioinorganic chemistryInorganic ChemistryBipyridinechemistry.chemical_compoundBiomimeticsMoleculeManganèsPhysical and Theoretical ChemistryMaterialsComputingMilieux_MISCELLANEOUSchemistry.chemical_classificationManganese010405 organic chemistryPhotoelectron SpectroscopyMesoporous silicaQuímica bioinorgànicaCatalaseSilicon Dioxide0104 chemical sciences[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistryCrystallographyLligandschemistryHybrid materialDimerization

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Bioinspired manganese(II) complexes with a clickable ligand for immobilisation on a solid support.

2014

International audience; Clickable ligands like N,N′-bis((pyridin-2-yl)methyl)prop-2-yn-1-amine (L1) and N-((1-methyl-1H-imidazol-2-yl)methyl)-N-(pyridin-2-ylmethyl)prop-2-yn-1-amine (L2) have been used to synthesise a series of manganese(II) complexes for grafting onto appropriate solid supports. These ligands mimic the 2-His-1-carboxylate facial chelation present in the active site of the manganese-dependent dioxygenase (MndD), while the alkyne side function allows grafting of the ligand onto an azido-functionalised support using “click chemistry” methodologies. Such synthetic analogues of the MndD crystallise in the solid state as double halide or pseudohalide-bridged dinuclear manganese(…

Models MolecularStereochemistryMolecular ConformationAlkynechemistry.chemical_elementManganese[CHIM.INOR]Chemical Sciences/Inorganic chemistry010402 general chemistryCrystallography X-RayLigands01 natural scienceslaw.inventionDioxygenasesInorganic ChemistrylawCoordination ComplexesCatalytic DomainPolymer chemistryChelationElectron paramagnetic resonanceSolid-Phase Synthesis Techniqueschemistry.chemical_classificationManganesebiology010405 organic chemistryLigand[CHIM.ORGA]Chemical Sciences/Organic chemistryElectron Spin Resonance SpectroscopyActive site[CHIM.CATA]Chemical Sciences/Catalysis[CHIM.MATE]Chemical Sciences/Material chemistrySilicon Dioxide0104 chemical scienceschemistrySuperexchangebiology.proteinClick chemistryClick ChemistryDalton transactions (Cambridge, England : 2003)

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CCDC 911104: Experimental Crystal Structure Determination

2014

Related Article: Jérémy Chaignon, Salah-Eddine Stiriba, Francisco Lloret, Consuelo Yuste, Guillaume Pilet, Laurent Bonneviot, Belén Albela, Isabel Castro|2014|Dalton Trans.|43|9704|doi:10.1039/C3DT53636J

Space GroupCrystallographybis(mu2-bromo)-bis(NN-bis((pyridin-2-yl)methyl)prop-2-yn-1-amine)-dibromo-di-manganeseCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates

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CCDC 911105: Experimental Crystal Structure Determination

2014

Space GroupCrystallographybis(mu2-azido)-diazido-bis(N-((1-methylimidazol-2-yl)methyl)-N-((pyridin-2-yl)methyl)prop-2-yn-1-amine)-di-manganese(ii)Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates

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CCDC 1040032: Experimental Crystal Structure Determination

2015

Related Article: Luis Escriche-Tur, Montserrat Corbella, Mercè Font-Bardia, Isabel Castro, Laurent Bonneviot, and Belén Albela|2015|Inorg.Chem.|54|10111|doi:10.1021/acs.inorgchem.5b01425

Space GroupCrystallographybis(mu2-2-Methoxybenzato-OO')-(mu2-oxo)-aqua-bis(22'-bipyridine)-(nitrato-O)-di-manganese nitrate acetonitrile solvate monohydrateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates

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CCDC 911106: Experimental Crystal Structure Determination

2014

bis(mu2-azido)-bis(azido)-bis(NN-bis((pyridin-2-yl)methyl)prop-2-yn-1-amine)-di-manganese(ii) methanol solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates

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CCDC 905065: Experimental Crystal Structure Determination

2014

Space GroupCrystallographybis(mu2-chloro)-bis(NN-bis((pyridin-2-yl)methyl)prop-2-yn-1-amine)-dichloro-di-manganese(ii)Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates

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CCDC 1040033: Experimental Crystal Structure Determination

2015

Related Article: Luis Escriche-Tur, Montserrat Corbella, Mercè Font-Bardia, Isabel Castro, Laurent Bonneviot, and Belén Albela|2015|Inorg.Chem.|54|10111|doi:10.1021/acs.inorgchem.5b01425

bis(mu2-2-Methoxybenzoato-OO')-(mu2-oxo)-aqua-bis(22'-bipyridine)-(perchlorato-O)-di-manganese(iii) perchlorate acetonitrile solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates

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