0000000001312865
AUTHOR
Pesce Maurizio
Dataset related to the article "Reduction of Cardiac Fibrosis by Interference With YAP-Dependent Transactivation"
This record contains raw data related to the article "Reduction of Cardiac Fibrosis by Interference With YAP-Dependent Transactivation". Abstract Background: Conversion of cardiac stromal cells into myofibroblasts is typically associated with hypoxia conditions, metabolic insults, and/or inflammation, all of which are predisposing factors to cardiac fibrosis and heart failure. We hypothesized that this conversion could be also mediated by response of these cells to mechanical cues through activation of the Hippo transcriptional pathway. The objective of the present study was to assess the role of cellular/nuclear straining forces acting in myofibroblast differentiation of cardiac stromal ce…
Dataset related to the article "LITHOTRIPSY OF CALCIFIED AORTIC VALVE LEAFLETS BY A NOVEL ULTRASOUND TRANSCATHETER-BASED DEVICE"
This record contains raw data related to the article “LITHOTRIPSY OF CALCIFIED AORTIC VALVE LEAFLETS BY A NOVEL ULTRASOUND TRANSCATHETER-BASED DEVICE” The increasing incidence of calcific aortic valve disease necessitates the elaboration of new strategies to retard the progression of the pathology with an innovative solution. While the increasing diffusion of the transcatheter aortic valve replacements (TAVRs) allows a mini-invasive approach to aortic valve substitution as an alternative to conventional surgical replacement (SAVR) in an always larger patient population, TAVR implantation still has contraindications for young patients. In addition, it is liable to undergo calcification with …