0000000001313482

AUTHOR

Gabriella Lindgren

showing 7 related works from this author

Signatures of selection in the genome of Swedish warmblood horses selected for sport performance

2019

Abstract Background A growing demand for improved physical skills and mental attitude in modern sport horses has led to strong selection for performance in many warmblood studbooks. The aim of this study was to detect genomic regions with low diversity, and therefore potentially under selection, in Swedish Warmblood horses (SWB) by analysing high-density SNP data. To investigate if such signatures could be the result of selection for equestrian sport performance, we compared our SWB SNP data with those from Exmoor ponies, a horse breed not selected for sport performance traits. Results The genomic scan for homozygous regions identified long runs of homozygosity (ROH) shared by more than 85%…

MaleGenotyping TechniquesPerformanceDIVERSITYBreedingRuns of HomozygosityHorseGenomeHISTORYInbreedingHOMOZYGOSITYGenetics & Heredity0303 health sciencesSnp dataeducation.field_of_studyHomozygoteRUNSASSOCIATIONGenomics04 agricultural and veterinary sciencesBreedDIFFERENTIATIONWarmbloodFemaleLife Sciences & BiomedicineTRAITSResearch ArticleSportsBiotechnologyGENESlcsh:QH426-470lcsh:BiotechnologyPopulationBiologyRuns of homozygosityPolymorphism Single Nucleotide03 medical and health scienceslcsh:TP248.13-248.65GeneticsAnimalsHorsesFunctional studieseducationSelection (genetic algorithm)030304 developmental biologyScience & Technology0402 animal and dairy scienceSelection signature040201 dairy & animal sciencelcsh:GeneticsBiotechnology & Applied MicrobiologyEvolutionary biologyWIDE SCANHaplotype homozygosityBMC Genomics
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MOESM5 of Signatures of selection in the genome of Swedish warmblood horses selected for sport performance

2019

Additional file 5: Table S3. SNP markers found to be under potential selection when analysed by the XPEHH test before FDR control.

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MOESM4 of Signatures of selection in the genome of Swedish warmblood horses selected for sport performance

2019

Additional file 4: Table S2. Details on the five overrepresented biological processes and the genes involved in each biological term from the ROH analysis.

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MOESM2 of Signatures of selection in the genome of Swedish warmblood horses selected for sport performance

2019

Additional file 2: Fig. S2. Distribution in frequency class of Fixation index (Fst) between SWB horses and Exmoor ponies.

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MOESM3 of Signatures of selection in the genome of Swedish warmblood horses selected for sport performance

2019

Additional file 3: Table S1. Genes located within consensus homozygous segments in Exmoor ponies.

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MOESM6 of Signatures of selection in the genome of Swedish warmblood horses selected for sport performance

2019

Additional file 6: Table S4. Details on the six overrepresented biological processes and the genes involved in each biological term from the overlapping regions from the XPEHH and Fst tests.

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MOESM1 of Signatures of selection in the genome of Swedish warmblood horses selected for sport performance

2019

Additional file 1: Fig. S1. Incidence of each single nucleotide polymorphism (SNP) in ROH in the SWB horses and Exmoor ponies. Genomic positions highlighted in green represent SNPs in a homozygous segment shared in over 85% of the SWB horses (a) and Exmoor ponies (b). The blue line shows the threshold for SNPs present in more than 80% of the horses and the red line shows the average value (22%) of SNP incidence in homozygous segment in SWB horses and (51%) in Exmoor ponies.

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