0000000001313624

AUTHOR

Paloma Bernal-albert

showing 4 related works from this author

Gold(I)-Catalyzed Intermolecular Cycloaddition of Allenamides with α,β-Unsaturated Hydrazones: Efficient Access to Highly Substituted Cyclobutanes

2014

α,β-Unsaturated N,N-dialkyl hydrazones undergo a mild [2 + 2] cycloaddition to allenamides when treated with a suitable gold catalyst. The method, which represents the first application of N,N-dialkyl hydrazones in gold catalysis, is compatible with a wide variety of substituents at the alkenyl moiety of the hydrazone component, proceeds with excellent levels of regio- and diastereoselectivity, and provides densely substituted cyclobutanes with good to excellent yields.

CyclobutanesLetterHydrazoneStereoisomerismBiochemistryMedicinal chemistryCatalysisCatalysisCombinatorial Chemistry TechniquesMoleculeOrganic chemistryMoietyPhysical and Theoretical ChemistryCycloadditionchemistry.chemical_classificationCycloaddition ReactionMolecular StructureOrganic ChemistryIntermolecular forceHydrazonesStereoisomerismAllenamidesCycloaddition3. Good healthAlkadienes:Investigación::23 Química [Materias]chemistryGoldCyclobutanes
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ChemInform Abstract: Gold(I)-Catalyzed Intermolecular Cycloaddition of Allenamides with α,β-Unsaturated Hydrazones: Efficient Access to Highly Substi…

2015

α,β-Unsaturated N,N-dialkyl hydrazones undergo a mild [2 + 2] cycloaddition to allenamides when treated with a suitable gold catalyst. The method, which represents the first application of N,N-dialkyl hydrazones in gold catalysis, is compatible with a wide variety of substituents at the alkenyl moiety of the hydrazone component, proceeds with excellent levels of regio- and diastereoselectivity, and provides densely substituted cyclobutanes with good to excellent yields.

chemistry.chemical_classificationCyclobutaneschemistryIntermolecular forceHydrazoneMoietyGeneral MedicineMedicinal chemistryCycloadditionCatalysisChemInform
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CCDC 1029359: Experimental Crystal Structure Determination

2015

Related Article: Paloma Bernal-Albert, Hélio Faustino, Ana Gimeno, Gregorio Asensio, José L. Mascareñas, and Fernando López|2014|Org.Lett.|16|6196|doi:10.1021/ol503121q

Space GroupCrystallographyCrystal System3-((2-(diisopropylcarbonohydrazonoyl)-2-methyl-3-phenylcyclobutylidene)methyl)-13-oxazolidin-2-oneCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1029358: Experimental Crystal Structure Determination

2015

Related Article: Paloma Bernal-Albert, Hélio Faustino, Ana Gimeno, Gregorio Asensio, José L. Mascareñas, and Fernando López|2014|Org.Lett.|16|6196|doi:10.1021/ol503121q

Space GroupCrystallographyCrystal System3-((2-(dimethylcarbonohydrazonoyl)-3-(4-methoxyphenyl)cyclobutylidene)methyl)-13-oxazolidin-2-oneCrystal StructureCell ParametersExperimental 3D Coordinates
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