0000000001313690

AUTHOR

Héctor Fernández-pérez

showing 2 related works from this author

Access to α-Aminophosphonic Acid Derivatives and Phosphonopeptides by [Rh(P–OP)]-Catalyzed Stereoselective Hydrogenation

2020

The hydrogenation of N-substituted vinylphosphonates using rhodium complexes derived from P–OP ligands L1, ent-L1, or (R,R)-Me-DuPHOS as catalysts has been successfully accomplished, achieving very high levels of stereoselectivity (up to 99% ee or de). The described synthetic strategy allowed for the efficient preparation of α-aminophosphonic acid derivatives and phosphonopeptides, which are valuable building blocks for the preparation of biologically relevant molecules.

010405 organic chemistryChemistryLigandOrganic Chemistrychemistry.chemical_element010402 general chemistry01 natural sciencesMedicinal chemistry0104 chemical sciencesCatalysisRhodiumDerivative (finance)MoleculeStereoselectivityJournal of Organic Chemistry
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CCDC 1996308: Experimental Crystal Structure Determination

2022

Related Article: Héctor Fernández-Pérez, Pawel Lenartowicz, Lucas Carreras, Arnald Grabulosa, Pawel Kafarski, Anton Vidal-Ferran|2020|J.Org.Chem.|85|14779|doi:10.1021/acs.joc.0c00914

Space GroupCrystallographyN-[1-(diethoxyphosphoryl)ethyl]-Nalpha-(trifluoroacetyl)phenylalaninamideCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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