The impact of conversion on the risk of major complication following laparoscopic colonic surgery: an international, multicentre prospective audit.

BACKGROUND: Laparoscopy has now been implemented as a standard of care for elective colonic resection around the world. During the adoption period, studies showed that conversion may be detrimental to patients, with poorer outcomes than both laparoscopic completed or planned open surgery. The primary aim of this study was to determine whether laparoscopic conversion was associated with a higher major complication rate than planned open surgery in contemporary, international practice.METHODS: Combined analysis of the European Society of Coloproctology 2017 and 2015 audits. Patients were included if they underwent elective resection of a colonic segment from the caecum to the rectosigmoid jun…

A comparative empirical assessment of roundabouts operations in rural areas: impacts on congestion-specific vehicle speed profiles, pollutant and noise emissions

Increasing concern about global warming and air quality has meant an increasing use of energetic and environmental indicators in roundabout design. The main objective of this paper is to compare different rural roundabouts in terms of traffic performance, pollutant and noise emissions through an integrated empirical assessment. Field measurements were carried out with a light duty vehicle in single-lane (SL), compact two-lane (CTL) and multi-lane (ML) roundabouts using Portable Emission Measurements Systems, OBD scan tool and Sound Level Meter, to measure real-world exhaust emissions, engine activity and acoustic data, respectively. Road traffic scene at roundabouts were obtained from video…

Evaluating the incidence of pathological complete response in current international rectal cancer practice: the barriers to widespread safe deferral of surgery

INTRODUCTION: The mainstay of management for locally advanced rectal cancer is chemoradiotherapy followed by surgical resection. Following chemoradiotherapy, a complete response may be detected clinically and radiologically (cCR) prior to surgery or pathologically after surgery (pCR). We aim to report the overall complete pathological response (pCR) rate and the reliability of detecting a cCR by conventional pre-operative imaging.METHODS: A pre-planned analysis of the European Society of Coloproctology (ESCP) 2017 audit was performed. Patients treated by elective rectal resection were included. A pCR was defined as a ypT0 N0 EMVI negative primary tumour; a partial response represented any r…

An international multicentre prospective audit of elective rectal cancer surgery; operative approach versus outcome, including transanal total mesorectal excision (TaTME)

Introduction: Transanal total mesorectal excision (TaTME) has rapidly emerged as a novel approach for rectal cancer surgery. Safety profiles are still emerging and more comparative data is urgently needed. This study aimed to compare indications and short-term outcomes of TaTME, open, laparoscopic, and robotic TME internationally. Methods: A pre-planned analysis of the European Society of Coloproctology (ESCP) 2017 audit was performed. Patients undergoing elective total mesorectal excision (TME) for malignancy between 1 January 2017 and 15 March 2017 by any operative approach were included. The primary outcome measure was anastomotic leak. Results: Of 2579 included patients, 76.2% (1966/257…

Platform session

CCDC 778567: Experimental Crystal Structure Determination

Related Article: G.M.Espallargas, A.J.Florence, J.van de Streek, L.Brammer|2011|CrystEngComm|13|4400|doi:10.1039/c1ce05222e