Author: Jolanta ŚWiątek-kozłowska

0000000001317649

AUTHOR

Jolanta ŚWiątek-kozłowska

showing 3 related works from this author

CH vs. HC—Promiscuous Metal Sponges in Antimicrobial Peptides and Metallophores

2023

Histidine and cysteine residues, with their imidazole and thiol moieties that deprotonate at approximately physiological pH values, are primary binding sites for Zn(II), Ni(II) and Fe(II) ions and are thus ubiquitous both in peptidic metallophores and in antimicrobial peptides that may use nutritional immunity as a way to limit pathogenicity during infection. We focus on metal complex solution equilibria of model sequences encompassing Cys–His and His–Cys motifs, showing that the position of histidine and cysteine residues in the sequence has a crucial impact on its coordination properties. CH and HC motifs occur as many as 411 times in the antimicrobial peptide database, while …

metal coordinationOrganic ChemistryPharmaceutical ScienceAnalytical Chemistrybioinorganic chemistryantimicrobial peptidesthermodynamicspotentiometryChemistry (miscellaneous)Drug DiscoveryMolecular Medicinebioinorganic chemistry; antimicrobial peptides; metallophores; thermodynamics; potentiometry; metal coordinationmetallophoresPhysical and Theoretical ChemistryMolecules

researchProduct

CCDC 1935968: Experimental Crystal Structure Determination

2022

Related Article: Paweł Lenartowicz, Danuta Witkowska, Beata Żyszka-Haberecht, Błażej Dziuk, Krzysztof Ejsmont, Jolanta Świątek-Kozłowska, Paweł Kafarski|2020|RSC Advances|10|24045|doi:10.1039/D0RA03764H

Space GroupCrystallographyCrystal Systemdiethyl (1-{[(benzyloxy)carbonyl]amino}ethenyl)phosphonateCrystal StructureCell ParametersExperimental 3D Coordinates

researchProduct

CCDC 1935969: Experimental Crystal Structure Determination

2022

Related Article: Paweł Lenartowicz, Danuta Witkowska, Beata Żyszka-Haberecht, Błażej Dziuk, Krzysztof Ejsmont, Jolanta Świątek-Kozłowska, Paweł Kafarski|2020|RSC Advances|10|24045|doi:10.1039/D0RA03764H

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersN2-(t-butoxycarbonyl)-N-[1-(diethoxyphosphoryl)ethenyl]glycinamideExperimental 3D Coordinates

researchProduct

PEPhysical Sciences and Engineering
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