0000000001317795
AUTHOR
Ivana Bušelić
showing 5 related works from this author
Additional file 2: Figure S2. of Anisakis pegreffii (Nematoda: Anisakidae) products modulate oxidative stress and apoptosis-related biomarkers in hum…
2016
Western blotting of (a) p53, (b) hsp70 and (c) TNF proteins detected in normal fibroblast HS-68 cell lines after 48 h exposure to a 0.1% concentration of Anisakis excretory/secretory (ES) and crude extract (EC) products: Lane 1: control; Lane 2: ES exposure; Lane 3: EC exposure, Std, mix of standard proteins as molecular markers. *P
Additional file 2: Figure S2. of Anisakis pegreffii (Nematoda: Anisakidae) products modulate oxidative stress and apoptosis-related biomarkers in hum…
2016
Western blotting of (a) p53, (b) hsp70 and (c) TNF proteins detected in normal fibroblast HS-68 cell lines after 48 h exposure to a 0.1% concentration of Anisakis excretory/secretory (ES) and crude extract (EC) products: Lane 1: control; Lane 2: ES exposure; Lane 3: EC exposure, Std, mix of standard proteins as molecular markers. *P
Efficiency of Target Larvicides Is Conditioned by ABC-Mediated Transport in the Zoonotic Nematode Anisakis pegreffii
2018
Anisakiasis is among the most significant emerging foodborne parasitoses contracted through consumption of thermally unprocessed seafood harboring infective Anisakis species larvae. The efficacy of the currently applied anthelminthic therapy in humans and in model organisms has not proven sufficient, so alternative solutions employing natural compounds combined with chemical inhibitors should be explored. By testing toxicity of the natural monoterpenes nerolidol and farnesol and the conventional anthelminthics abamectin and levamisole in the presence/absence of MK-571 and Valspodar, which inhibit the ABC transporter proteins multidrug resistance protein (MRP-like) and P-glycoprotein (P-gp),…
Anisakis pegreffii (Nematoda: Anisakidae) products modulate oxidative stress and apoptosis-related biomarkers in human cell lines
2016
Background In countries with elevated prevalence of zoonotic anisakiasis and high awareness of this parasitosis, a considerable number of cases that associate Anisakis sp. (Nematoda, Anisakidae) and different bowel carcinomas have been described. Although neoplasia and embedded larvae were observed sharing the common site affected by chronic inflammation, no association between the nematode and malignancy were directly proved. Similarly, no data are available about the effect of secretory and excretory products of infecting larvae at the host’s cellular level, except in respect to allergenic interaction. Methods To test the mechanisms by which human non-immune cells respond to the larvae, w…
Additional file 1: Figure S1. of Anisakis pegreffii (Nematoda: Anisakidae) products modulate oxidative stress and apoptosis-related biomarkers in hum…
2016
Regression analysis between cells vitality and ROS production at 48 h in control cells (CO) and after treatment with excretory/secretory (ES) and crude extract (EC) products (n = 9 for each treatment). (TIF 179 kb)