0000000001319876

AUTHOR

ÁRpád Csőr

showing 3 related works from this author

Stereoselective synthesis of carane-based chiral β- and γ-amino acid derivatives via conjugate addition

2015

Abstract Michael addition of dibenzylamine to (−)-tert-butyl isochaminate, prepared in three steps from (−)-perillaldehyde, furnished a carane-based β-amino acid derivative in a highly stereospecific reaction. The resulting amino ester was transformed to the bicyclic amino acid, a promising building block for the synthesis of 1,3-heterocycles and peptidomimetics. The conjugate addition of nitromethane to α,β-unsaturated methyl ester likewise resulted in nitro esters in stereospecific reactions. Catalytic reduction of the nitro group yielded a γ-amino ester. Under acidic conditions, the hydrolysis of the methyl ester resulted in an unexpected aminolactone-type product through rearrangement o…

chemistry.chemical_classificationNitromethaneBicyclic moleculeStereochemistryOrganic ChemistryEnantioselective synthesisBiochemistryAmino acidHydrolysischemistry.chemical_compoundStereospecificitychemistryDrug DiscoveryNitroMichael reactionamino acid derivativesta116stereoselective synthesiscaraneTetrahedron
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CCDC 1040501: Experimental Crystal Structure Determination

2015

Related Article: Zsolt Szakonyi, Árpád Csőr, Matti Haukka, Ferenc Fülöp|2015|Tetrahedron|71|4846|doi:10.1016/j.tet.2015.05.019

Space GroupCrystallography(22-dimethyl-4-oxo-3-oxabicyclo[3.3.1]non-9-yl)methanaminium chlorideCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1040500: Experimental Crystal Structure Determination

2015

Related Article: Zsolt Szakonyi, Árpád Csőr, Matti Haukka, Ferenc Fülöp|2015|Tetrahedron|71|4846|doi:10.1016/j.tet.2015.05.019

3-carboxy-77-dimethylbicyclo[4.1.0]heptan-2-aminium chlorideSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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