0000000001320360

AUTHOR

Angélique Lascaux

showing 3 related works from this author

Selective recognition of neutral guests in an aqueous medium by a biomimetic calix[6]cryptamide receptor

2015

The design of artificial receptors that can efficiently work in water is a challenging research area. A possible biomimetic approach for the elaboration of such receptors consists of associating a hydrophobic cavity with a polar polyfunctional binding site. On this basis, a hydrophilic calix[6]cryptamide decorated with oligo(ethylene glycol) units (i.e. 8) was synthesized through an efficient [1 + 1] macrocyclization reaction as the key-step. The complexation of neutral molecules was evaluated by NMR spectroscopy through competition experiments either in apolar or aqueous media. In both media, host 8 can bind neutral species that display H-bonding acceptor and donor groups such as amides or…

Models MolecularEthylene GlycolMagnetic Resonance SpectroscopyStereochemistryAllosteric regulationMolecular ConformationCrystallography X-Ray010402 general chemistry01 natural sciencesBiochemistrychemistry.chemical_compoundBiomimetic MaterialsCalixareneUreaMoleculeaqueous mediumartificial receptorsbiomimeticsPhysical and Theoretical ChemistryBinding siteta116010405 organic chemistryHydrogen bondOrganic ChemistryWaterHydrogen BondingNuclear magnetic resonance spectroscopyAmidesAcceptor0104 chemical scienceschemistryCyclizationCalixarenesHydrophobic and Hydrophilic InteractionsEthylene glycolOrganic & Biomolecular Chemistry
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CCDC 1428619: Experimental Crystal Structure Determination

2015

Related Article: Angélique Lascaux, Gaël De Leener, Luca Fusaro, Filip Topić, Kari Rissanen, Michel Luhmer, Ivan Jabin|2016|Org.Biomol.Chem.|14|738|doi:10.1039/C5OB02067K

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates3915354156-hexa-t-butyl-526061-trimethoxy-193146-trioxa-22252849-tetraazanonacyclo[23.19.7.71733.1711.13943.15458.0545.01318.03237]henhexaconta-1(45)247(60)81013151732343639(52)404254(61)5557-octadecaene-232750-trione calix[6]cryptamide imidazolidin-2-one chloroform diisopropyl ether solvate
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CCDC 1428618: Experimental Crystal Structure Determination

2015

Related Article: Angélique Lascaux, Gaël De Leener, Luca Fusaro, Filip Topić, Kari Rissanen, Michel Luhmer, Ivan Jabin|2016|Org.Biomol.Chem.|14|738|doi:10.1039/C5OB02067K

Space GroupCrystallographyCrystal SystemCrystal Structure3915354156-hexa-t-butyl-526061-trimethoxy-193146-trioxa-22252849-tetraazanonacyclo[23.19.7.71733.1711.13943.15458.0545.01318.03237]henhexaconta-1(45)247(60)81013151732343639(52)404254(61)5557-octadecaene-232750-trione calix[6]cryptamide imidazolidin-2-one chloroform pentane solvateCell ParametersExperimental 3D Coordinates
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