Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019

Background Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019. Methods 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal Gaussian…

Rapidity dependence of initial state geometry and momentum correlations in p+Pb collisions

Event geometry and initial state correlations have been invoked as possible explanations of long range azimuthal correlations observed in high multiplicity p+p and p+Pb collisions. We study the rapidity dependence of initial state momentum correlations and event-by-event geometry in $\sqrt{s}=5.02~\rm{TeV}$ p+Pb collisions within the 3+1D IP-Glasma model~\cite{Schenke:2016ksl}, where the longitudinal structure is governed by JIMWLK rapidity evolution of the incoming nuclear gluon distributions. We find that the event geometry is correlated across large rapidity intervals whereas initial state momentum correlations are relatively short range in rapidity. Based on our results, we discuss impl…

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

Autoantibodies in complex regional pain syndrome bind to a differentiation-dependent neuronal surface autoantigen.

Complex regional pain syndrome, which is characterised by pain and trophic disturbances, develops frequently after peripheral limb trauma. There is an increasing evidence of an involvement of the immune system in CRPS, and recently we showed that CRPS patients have autoantibodies against nervous system structures. Therefore we tested the sera of CRPS patients, neuropathy patients and healthy volunteers for surface-binding autoantibodies to primary cultures of autonomic neurons and differentiated neuroblastoma cell lines using flow cytometry. Thirteen of 30 CRPS patients, but none of 30 healthy controls and only one of the 20 neuropathy sera had specific surface binding to autonomic neurons …

Improved measurement of the 02+→01+ E0 transition strength for 72Se using the SPICE spectrometer

The selenium isotopes lie at the heart of a tumultuous region of the nuclear chart where shape coexistence effects grapple with neutron-proton pairing correlations, triaxiality, and the impending proton drip line. In this work, a study of 72Se by internal conversion electron and γ-ray spectroscopy was undertaken with the SPICE and TIGRESS arrays. New measurements of the branching ratio and lifetime of the 02+ state were performed, yielding a determination of ρ2(E0;02+→01+)=29(3) milliunits. Two-state mixing calculations were performed that highlighted the importance of interpretation of such E0 strength values in the context of shape coexistence. peerReviewed

Five insights from the Global Burden of Disease Study 2019

The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD …

T241 INCREASED PREVALENCE OF NON-ORGAN SPECIFIC AUTOANTIBODIES IN COMPLEX REGIONAL PAIN SYNDROME

Direct measurement of the W boson width

We present a direct measurement of the width of the W boson using the shape of the transverse mass distribution of W->enu candidates selected in 1 fb-1 of data collected with the D0 detector at the Fermilab Tevatron collider in ppbar collisions at sqrt{s}=1.96 TeV. We use the same methods and data sample that were used for our recently published W boson mass measurement, except for the modeling of the recoil, which is done with a new method based on a recoil library. Our result, 2.028 +- 0.072 GeV, is in agreement with the predictions of the standard model.

CCDC 757617: Experimental Crystal Structure Determination

Related Article: T.S.B.Baul, A.Paul, L.Pellerito, M.Scopelliti, C.Pellerito, P.Singh, P.Verma, A.Duthie, D.de Vos, R.P.Verma, U.Englert|2010|J.Inorg.Biochem.|104|950|doi:10.1016/j.jinorgbio.2010.05.001