0000000001322700

AUTHOR

B. Krishnan

showing 4 related works from this author

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
researchProduct

A first search for coincident gravitational waves and high energy neutrinos using LIGO, Virgo and ANTARES data from 2007

2013

A search for high-energy neutrinos coming from the direction of the Sun has been performed using the data recorded by the ANTARES neutrino telescope during 2007 and 2008. The neutrino selection criteria have been chosen to maximize the selection of possible signals produced by the self-annihilation of weakly interacting massive particles accumulated in the centre of the Sun with respect to the atmospheric background. After data unblinding, the number of neutrinos observed towards the Sun was found to be compatible with background expectations. The 90% CL upper limits in terms of spin-dependent and spin-independent WIMP-proton cross-sections are derived and compared to predictions of two sup…

AstrofísicaEXPLOSIONSHigh energyPhotonPOINT SOURCESSUPERCONDUCTING COSMIC STRINGSGravitational waves / experimentsGravitational waves/experimentsAstrophysics01 natural scienceshigh energy neutrinosgravitational wavesgravitational waves / experiment010303 astronomy & astrophysicsQCmedia_commonLine (formation)QBPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)GAMMA-RAY BURSTSdark matter detectorsGravitational waves / experiments; Neutrino astronomy; Astronomy and Astrophysicshigh energy neutrinos[SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]Settore FIS/01 - Fisica SperimentaleAstrophysics::Instrumentation and Methods for Astrophysicsgravitational waves; gravitational waves / experiments; neutrino astronomy; high energy neutrinos; high energy neutrinosgravitational wavesgravitational wavesparticle physics - cosmology connectionNeutrino astronomyCOSMIC STRINGSRELATIVISTIC JETSNeutrinoAstrophysics - High Energy Astrophysical Phenomenasupersymmetry and cosmology[PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]gravitational waves / experiments; neutrino astronomyTELESCOPEmedia_common.quotation_subjectAstrophysics::High Energy Astrophysical PhenomenaSCIENCE RUNFOS: Physical sciencesddc:500.2GAMMA-RAY BURSTS; CORE-COLLAPSE SUPERNOVAE; SUPERCONDUCTING COSMIC STRINGS; MAGNETAR GIANT FLARES; SCIENCE RUN; RELATIVISTIC JETS; POINT SOURCES; BLACK-HOLES; LOCAL-RATE; TELESCOPEGravitational wavesGeneral Relativity and Quantum CosmologyCORE-COLLAPSE SUPERNOVAESettore FIS/05 - Astronomia e AstrofisicaCoincidentneutrino experiments0103 physical sciences010306 general physicsMAGNETAR GIANT FLARESBLACK-HOLESHigh Energy Astrophysical PhenomenaGravitational waveAstronomy[ PHYS.ASTR.HE ] Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]Astronomy and AstrophysicsDRIVENUniverseLIGOGIANT FLARESLOCAL-RATEFISICA APLICADALUMINOSITYRADIATIONHigh Energy Physics::Experiment[ SDU.ASTR.HE ] Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]Experiments[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
researchProduct

A Fermi Gamma-Ray Burst Monitor Search for Electromagnetic Signals Coincident with Gravitational-wave Candidates in Advanced LIGO's First Observing R…

2019

We present a search for prompt gamma-ray counterparts to compact binary coalescence gravitational wave (GW) candidates from Advanced LIGO's first observing run (O1). As demonstrated by the multimessenger observations of GW170817/GRB 170817A, electromagnetic and GW observations provide complementary information about the astrophysical source and, in the case of weaker candidates, may strengthen the case for an astrophysical origin. Here we investigate low-significance GW candidates from the O1 compact-binary coalescence searches using the Fermi Gamma-ray Burst Monitor (GBM), leveraging its all-sky and broad energy coverage. Candidates are ranked and compared to background to measure signific…

AstrofísicaGravitacióAstronomyAstrophysics::High Energy Astrophysical Phenomenagamma-ray burst: generalFOS: Physical sciencesAstrophysicsAstronomy & Astrophysicsgeneral [gamma-ray burst]01 natural sciencesCoincidenceCoincident0103 physical sciences010306 general physics010303 astronomy & astrophysicsgravitational waveSTFCQCQBHigh Energy Astrophysical Phenomena (astro-ph.HE)Settore FIS/01Physicsastro-ph.HEScience & TechnologySolar flareGravitational wavegamma-ray burst: general; gravitational waves; Astronomy and Astrophysics; Space and Planetary ScienceRCUKAstronomy and AstrophysicsAstronomy and AstrophysicLIGOPhysics and Astronomygravitational wavesSpace and Planetary SciencePhysical Sciencesgamma-ray burst: general; gravitational wavesgeneral; gravitational waves; Astronomy and Astrophysics; Space and Planetary Science [gamma-ray burst]False alarmAstrophysics - High Energy Astrophysical PhenomenaGamma-ray burst[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Fermi Gamma-ray Space Telescope
researchProduct

Search for GW signals associated with GRBs

2021

We present the results of targeted searches for gravitational-wave transients associated with gamma-ray bursts during the second observing run of Advanced LIGO and Advanced Virgo, which took place from 2016 November to 2017 August. We have analyzed 98 gamma-ray bursts using an unmodeled search method that searches for generic transient gravitational waves and 42 with a modeled search method that targets compact-binary mergers as progenitors of short gamma-ray bursts. Both methods clearly detect the previously reported binary merger signal GW170817, with p-values of <9.38x10^-6^ (modeled) and 3.1x10^-4^ (unmodeled). We do not find any significant evidence for gravitational-wave signals assoc…

Astrophysics and AstronomyGamma-ray astronomyhigh energy astrophysicsAstrophysics::High Energy Astrophysical PhenomenaPhysicsAstrophysics::Cosmology and Extragalactic Astrophysicsstellar astronomyGamma ray burstsGravitational wavesCosmologyobservational astronomyGamma ray astronomyGamma-ray burstsAstrophysical ProcessesNatural Sciences
researchProduct