Author: Simon Dochain

0000000001322946

AUTHOR

Simon Dochain

Combining organocatalysis and lanthanide catalysis: a sequential one-pot quadruple reaction sequence/hetero-Diels-Alder asymmetric synthesis of functionalized tricycles

A stereoselective one-pot synthesis of functionalized complex tricyclic polyethers has been achieved using the combination of secondary amine and lanthanide catalysis. This one-pot quadruple reaction/Hetero-Diels–Alder sequence gave good yields (per step) as well as excellent diastereo- and enantioselectivities. Furthermore, the particular combination of lanthanide complexes with organocatalysis is one of the first examples described for sequential catalysis.

research product

CCDC 1510190: Experimental Crystal Structure Determination

Related Article: Simon Dochain, Fabrizio Vetica, Rakesh Puttreddy, Kari Rissanen and Dieter Enders|2016|Angew.Chem.,Int.Ed.|55|16153|doi:10.1002/anie.201610196

research product

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