0000000001335534
AUTHOR
Schirò, G
THz spectroscopy study of amyloid fibrils
In suitable conditions proteins can modify their native conformation and associate to form aggregates with different morphologies in dependence on the external physico-chemical conditions. This phenomenon, one of the most challenging in life sciences, is associated with widely diffused pathologies such as Alzheimer’s, Parkinson’s and Creutzfeldt-Jacob’s diseases. Of particular relevance are ordered elongated aggregates with highly organized patterns of hydrogen-bonds, known as amyloid fibrils. While much biological and structural information are available about amyloids, and in spite of the fundamental paradigm of structure-dynamics-function relation in proteins, much less is known about th…
Ricerche nella catacomba di Villagrazia di Carini
The Quaderno Digitale 9 is dedicated to the archaeological researches conducted in the Early Christian catacomb of Villagrazia di Carini until year 2015. The essay of G. Schirò presents the results of the excavations carried out from 2008 to 2011 in the Gallery IX and the structural analysis of 36 burials. Marco Correra, in the second essay, presents the analysis of the types of closure of the tombs so far excavated, in comparison with other funerary contexts in Sicily, Sardinia and North Africa. Finally, Francesco Scirè and Marta Marescalchi illustrate the project drawn up for the enjoyment of the most representative sectors of the monument, whose visit was inaugurated in May 2015.