6533b7cefe1ef96bd1256e7f

RESEARCH PRODUCT

Metal ion-promoted activation of amino acid esters of carbohydrates in the synthesis of peptides

Horst KunzRichard Kullmann

subject

chemistry.chemical_classificationDipeptideMetal ions in aqueous solutionOrganic ChemistryLiquid phaseUronic acidCarbohydrateBiochemistryAmino acidMetalchemistry.chemical_compoundAminolysischemistryvisual_artDrug Discoveryvisual_art.visual_art_mediumOrganic chemistry

description

Abstract Carbohydrate esters 1 and 2 of N-protected amino acids are activated by coordination of metal ions and subjected to aminolysis by amino acid esters 3 to form peptides 4 .

https://doi.org/10.1016/s0040-4039(00)60020-5