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RESEARCH PRODUCT
Ion mobility spectrometry as a fast analytical tool in benzalkonium chloride homologs determination.
Sergio ArmentaM. De La GuardiaFrancesc A. Esteve-turrillasD. Gallart-mateusubject
Detection limitAqueous solutionChromatographyChemistryIon-mobility spectrometry010401 analytical chemistryAnalytical chemistry010501 environmental sciences01 natural sciencesSwimming pool water0104 chemical sciencesAnalytical ChemistryBenzalkonium chloridemedicineBAC determination0105 earth and related environmental sciencesmedicine.drugdescription
Abstract A novel procedure is proposed for the determination by ion mobility spectrometry (IMS) of C 12 , C 14 and C 16 benzalkonium chloride (BAC) homologs. The proposed method requires minimum sample treatment and the measurement was made in less than one minute. A high sensitivity was obtained for BAC determination by IMS with limit of detection values from 37 to 69 µg L −1 . Accuracy of the proposed methodology was evaluated through the analysis of aqueous and alcoholic samples spiked with BAC at concentration levels from 0.002% to 20% (w/v), providing recovery values from 91% to 104%. BAC was determined in sanitary alcohols, nasal sprays, postharvest products, algaecides, and treated swimming pool water. Results obtained by the proposed IMS methodology were statistically comparable to those provided by a liquid chromatography-ultraviolet (LC-UV) reference methodology. The Green Certificate evaluation of the proposed IMS methodology provided 91 score points in the Eco-Scale as compared with 77 for LC-UV method.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-03-01 | Talanta |