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RESEARCH PRODUCT

Saliva: Its value as a biological matrix and current methods of sampling

Giuseppina CampisiFalaschini SLorenzo Lo MuzioPaola Maria RocciaF. Di NicolaO. Di Fede

subject

0301 basic medicineSalivabiologylcsh:RImmunologylcsh:MedicineSampling (statistics)030206 dentistryDiseaseMatrix (chemical analysis)03 medical and health sciencesBiomarker030104 developmental biology0302 clinical medicinestomatognathic systemImmunologybiology.proteinClinical endpointImmunology and AllergyAntibodyDna viral

description

Saliva is a non-invasive medium, its analysis is useful to measure a wide range of hormones, drugs, narcotics, antibodies, host, microbial, fungal and viral DNA up to salivary mRNA; hence, it has been suggested to be an easy and reliable biomarker in disease diagnostics, such as inflammatory mouth infections/diseases, and in normal health surveillance. In light of this potential, our primary endpoint is to review the current knowledge on saliva analyses and its recent methods of sampling.

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