6533b7cffe1ef96bd1258432
RESEARCH PRODUCT
Highly Selective Detection of Nerve‐Agent Simulants with BODIPY Dyes
Andrea Barba-bonAndrea Barba-bonAnthony HarrimanSalvador GilFélix SancenónAna M. Costerosubject
Analytical chemistrysensorsCatalysischemistry.chemical_compoundQUIMICA ORGANICAfluorescent probesmedicinePhosphorylationColoring AgentsBoronFluorescent DyesNerve agentNeurological agentsMolecular StructurephosphorylationChemistryQUIMICA INORGANICAOrganic ChemistryGeneral ChemistryHighly selectiveCombinatorial chemistryFluorescenceBODIPYboronmedicine.drugdescription
Two chromo-fluorogenic probes, each based on the boron dipyrromethene core, have been developed for the detection of nerve-agent mimics. These chemosensors display both a color change and a significant enhancement of fluorescence in the presence of diethylcyanophosphonate (DCNP) and diisopropylfluorophosphate (DFP). No interference from other organophosphorus compounds or acids has been observed. Two portable chemosensor kits have been developed and tested to demonstrate its practical application in real-time monitoring.
year | journal | country | edition | language |
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2014-04-03 | Chemistry – A European Journal |