6533b7cffe1ef96bd1258d67

RESEARCH PRODUCT

ESRA19-0543 Analgesic effects of dexamethasone when given perineurally or intravenously in the upper arm bone fracture and shoulder joint surgery

subject

description

Background and aims Shoulder surgery is associated with severe pain. Pain delays rehabilitation and lowers quality of life. Finding adjuvants to the LA to improve analgesia and facilitate mobilization has been the focus of researchers recently. The aim of this work was to investigate which administration methods—dexamethasone perineural or intravenously—prevents pain more effectively. Methods Prospective, randomized study conducted at Hospital of Traumatology and Orthopaedics after ethics committee approval. Study involved 75 patients with upper limb fracture or shoulder joint surgery in RA and GA. Group I: Bupivacaine 0.25% 70 mg + Dexamethasone 8 mg perineurally Group II: Bupivacaine 0.25% 70 mg perineuraly + Dexamethasone 8 mg i/v. Group 0 (control): Bupivacaine 0.25% 70 mg perineurally The following indicators were fixed: pain intensity, morphine consumption, patient satisfaction. Statistical analysis was performed using SPSS software. Results Pain reliably (p The mean morphine consumption for the control group on D0 was significantly higher for Group 0: 26.4 mg, I -15.6 mg and 13.2 mg for group II (p In the control group, at first night, sleep disorders were more frequent (72.0%), but in group I only 12.0% and 4% in group II (p Conclusions The pain intensity and opioid is significantly lower in the dexamethasone groups, especially if systemically given. Postoperative period quality is significantly higher in dexamethasone groups.