6533b7cffe1ef96bd1258d6d

RESEARCH PRODUCT

Random Boolean networks response to external periodic signals

subject

description

Random Boolean networks have been proposed as discrete models of genetic networks. Depending on the values of their control parameters, these networks fall by themselves in order or disorder phases. These networks are autonomous systems: no external inputs are considered. Nevertheless, in the real world the genetic networks are in5uenced by external signals. Many biological rhythms have 24-h periods related to sunlight, coupled with molecular clocks. In this work we study the response of Random Boolean Networks to analytical and non-analytical external periodic signals. The relationship between external and internal parameters for the determination of the dynamical behaviour of this networks is theoretically determined and simulations in agreement with these theoretical results are reported. c