6533b7cffe1ef96bd1258ea3

RESEARCH PRODUCT

Exploiting the Opportunity to Use Plant-Derived Nanoparticles as Delivery Vehicles

Vincenza TinnirelloNima Rabienezhad GanjiCarine De Marcos LousaRiccardo AlessandroStefania Raimondo

subject

sonicationco-incubationEcologymicroRNAdrug deliveryplant-derived nanoparticles (PDNPs)Plant ScienceEcology Evolution Behavior and Systematics

description

The scientific community has become increasingly interested in plant-derived nanoparticles (PDNPs) over the past ten years. Given that they possess all the benefits of a drug carrier, including non-toxicity, low immunogenicity, and a lipid bilayer that protects its content, PDNPs are a viable model for the design of innovative delivery systems. In this review, a summary of the prerequisites for mammalian extracellular vesicles to serve as delivery vehicles will be given. After that, we will concentrate on providing a thorough overview of the studies investigating the interactions of plant-derived nanoparticles with mammalian systems as well as the loading strategies for encapsulating therapeutic molecules. Finally, the existing challenges in establishing PDNPs as reliable biological delivery systems will be emphasized.

yearjournalcountryeditionlanguage
2023-03-07
10.3390/plants12061207https://hdl.handle.net/10447/585791