6533b7cffe1ef96bd12591ec

RESEARCH PRODUCT

Iron(III) chloride as mild catalyst for the dearomatizing cyclization of N-acylindoles

Jingyu ZhangJing LiJas S WardKhai-nghi TruongKari RissanenMarkus Albrecht

subject

katalyytitkemialliset yhdisteetkatalyysiorgaaninen kemiaindoliini

description

A catalytic approach for the preparation of indolines by dearomatizing cyclization is presented. FeCl3 acts as a catalyst to afford tetracyclic 5a,6-dihydro-12H-indolo[2,1-b][1,3]benzoxazin-12-ones in good yields. The cyclization also proceeds with tosylamides forming C-N bonds in 53 % yield. peerReviewed

http://urn.fi/URN:NBN:fi:jyu-202009075768