6533b7cffe1ef96bd1259750
RESEARCH PRODUCT
Studies on (echinodermata) coelomocyte lysate I. Hemolytic activity of coelomocyte hemolysins
Donatella CiullaCalogero Canicattìsubject
LysisbiologyImmunologyHemolysinbiology.organism_classificationRed blood cellmedicine.anatomical_structureLytic cycleBiochemistryCell surface receptorImmunologymedicineHolothuriaSphingomyelinCoelomocyteDevelopmental Biologydescription
Abstract The Holothuria polii coelomocyte lysate contains two trypsin-resistant lytic proteins having different chemico-physical properties : a calcium dependent and heat-labile hemolysin that is probably a constitutive component of the coelomic fluid, and another calcium independent and heat-stable one that is released after immunological stimulation; it is therefore not detectable in natural conditions. The sphingomyelin seems to be the membrane receptor with which both hemolysins interact producing lysis.
year | journal | country | edition | language |
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1987-09-01 | Developmental & Comparative Immunology |