6533b7cffe1ef96bd1259989

RESEARCH PRODUCT

The contribution of epistasis to the architecture of fitness in an RNA virus

Rafael SanjuánSantiago F. ElenaAndrés Moya

subject

RNA virusesGeneticsDNA ComplementaryMultidisciplinarybiologyEpistasis and functional genomicsRNAEpistasis GeneticEvolutionary biologyRNA virusBiological Sciencesbiology.organism_classificationGenomeInteractions among genome componentsVesicular stomatitis virusFitnessFisher's geometric modelGenotypeMutagenesis Site-DirectedEpistasisRNA VirusesEpistasisCloning MolecularMutations

description

4 pages, 2 figures.-- PMID: 15492220 [PubMed].-- PMCID: PMC524436.-- Additional information (Suppl. table S1: Relevant information about each single- and double-nucleotide substitution mutant created) available at: http://www.pnas.org/content/101/43/15376/suppl/DC1

https://doi.org/10.1073/pnas.0404125101