6533b7d0fe1ef96bd1259e1c

RESEARCH PRODUCT

Genetic Network construction in CML gene expression profile data analysis

Luigi AugugliaroAngelo MineoG CammarataA. Santoro

subject

Gaussian graphical models modularity differentially expressed genes.

description

Aim of this paper is to define a new statistical framework to identify central modules in Gaussian Graphical Models (GGMs) estimated by gene expression data measured on a sample of patients with negative molecular response to imatinib. A central module is defined as a module of a GGM which contains genes that are defined differentially expressed.

http://hdl.handle.net/10447/44266