6533b7d0fe1ef96bd125a17e

RESEARCH PRODUCT

Iontophoresis for Therapeutic Drug Delivery and Non-invasive Sampling Applications

Virginia MerinoAlicia C. López CastellanoM. Begoña Delgado-charro

subject

IontophoresisLidocainebusiness.industryFentanyl03 medical and health sciencesSumatriptan0302 clinical medicineAnesthesiaDrug delivery030221 ophthalmology & optometryMedicinebusinessNon invasive sampling030217 neurology & neurosurgerymedicine.drugTransdermal

description

Most research concerning iontophoresis has focused on topical and transdermal drug delivery and in non-invasive skin sampling applications. Iontophoresis has been established as a safe, versatile and efficient enhancement technique, and several iontophoretic devices have been marketed for topical (lidocaine) and systemic (fentanyl, sumatriptan) delivery and for non-invasive sampling (glucose). Nevertheless, the last decade has seen an increased interest into the potential use of iontophoresis to deliver drugs through the nail and through the sclera and cornea, the two main barriers to eye drug delivery. This chapter aims to summarize the main progress achieved in these areas.

https://doi.org/10.1007/978-3-662-53273-7_6