6533b7d0fe1ef96bd125b046
RESEARCH PRODUCT
Low-loading asymmetric organocatalysis
Renato NotoMichelangelo GruttadauriaFrancesco GiacalonePaola Agrigentosubject
AminocatalysisMolecular StructureOrganic chemicalsBronsted BaseEnantioselective synthesisPillarSettore CHIM/06 - Chimica OrganicaGeneral ChemistryCatalysisBronsted acidCatalysisoragnocatalysichemistry.chemical_compoundchemistryphase-transfer catalysiOrganocatalysisOrganic chemistryLewis acids and basesOrganic ChemicalsBrønsted–Lowry acid–base theoryCarbenedescription
Asymmetric organocatalysis is now recognized as the third pillar of asymmetric synthesis. Recent years have witnessed increasing interest towards the use of highly active and stereoselective organocatalysts. This critical review documents the advances in the development of chiral organocatalysts which are systematically used in ≤3 mol% loading in all the sub-areas of the field, namely aminocatalysis, Brønsted acids and bases, Lewis acids and bases, hydrogen bond-mediated catalysis, phase transfer and N-heterocyclic carbene catalyses (194 references).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-12-15 | Chem. Soc. Rev. |