6533b7d0fe1ef96bd125b512
RESEARCH PRODUCT
Simplified first-trimester fetal cardiac screening (four chamber view and ventricular outflow tracts) in a low-risk population
Emanuela OrlandiC RossiAntonino PerinoG MusicòF. Orlandisubject
congenital heart diseasesSettore MED/40 - Ginecologia E Ostetriciadescription
Objectives Our aim was to assess the accuracy of a simplified fetal cardiac study, inclusive of four-chamber view (4CV) and ventricular outflow tracts, performed during the 11–14 week screening by well-trained obstetricians to detect congenital heart diseases (CHDs). Methods A transabdominal ultrasound was performed on 4820 singleton pregnant women at 11–14 weeks to visualize the visceral site, the 4CV, and the outflow tracts. Neonatal outcomes were recorded 6 and 12 months after birth. Results Among the 4820 patients reviewed, 790 were excluded because of loss at prenatal or postnatal follow-up (649 cases), or inability to obtain adequate first-trimester sonographic cardiac evaluation (141 cases). Among the 4030 included cases, 32 CHD cases were detected (20 major and 12 minor); 18 of the major (90%) and five of the minor (42%) were detected or suspected in the first trimester, one major and six minor in the second trimester, and one major and one minor only after birth. Conclusions A simplified protocol is an effective tool to screen for CHD at 11–14 weeks.
year | journal | country | edition | language |
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2014-01-01 |